NCT04954664 Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor
| NCT ID | NCT04954664 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Alabama at Birmingham |
| Condition | Dental Implant |
| Study Type | INTERVENTIONAL |
| Enrollment | 44 participants |
| Start Date | 2021-08-11 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 44 participants in total. It began in 2021-08-11 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor called Recombinant Human Platelet-Derived Growth Factor (rhPDGF).
Eligibility Criteria
Inclusion Criteria: * English speaking * At least 18 years old * Must be a patient of the UAB Dental School * Able to read and understand informed consent document * Need for implants to replace missing tooth or teeth in at least one quadrant of the mouth. * Insufficient alveolar ridge width for endosseous implant placement defined as 5mm or less as determined by bone sounding and cone beam computed tomography (CBCT) scan. Exclusion Criteria: * Non-English speaking * Less than 18 years old * Smokers/tobacco users (\>10 cigarettes/day) * Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing * Patient is a poor compliance risk (i.e., poor oral hygiene, history of alcohol or drug abuse) * Vertical loss of bone at edentulous ridge.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04954664 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 99 Years, studying Dental Implant. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04954664 currently recruiting?
Yes, NCT04954664 is actively recruiting participants. Contact the research team at basma86@uab.edu for enrollment information.
Where is the NCT04954664 trial being conducted?
This trial is being conducted at Birmingham, United States.
Who is sponsoring the NCT04954664 clinical trial?
NCT04954664 is sponsored by University of Alabama at Birmingham. The trial plans to enroll 44 participants.