← All Sponsors
SPONSOR

Sanofi

Total Trials
12
Recruiting
12
Phases
Phase 3, Phase 4, Phase 2

Sanofi is a French multinational pharmaceutical company and one of the world's five largest by revenue, with a global clinical development operation spanning immunology, oncology, rare diseases and blood disorders, vaccines, and consumer healthcare. Sanofi has a long legacy in diabetes (insulin glargine/Lantus was the world's best-selling insulin for over a decade), cardiovascular disease (alirocumab/Praluent for LDL reduction), and multiple sclerosis (teriflunomide/Aubagio, alemtuzumab/Lemtrada).

Sanofi's research transformation in recent years has concentrated investment heavily on immunology and inflammation — particularly the dupilumab program co-developed with Regeneron — and on rare blood disorders and oncology. In oncology, cemiplimab (Libtayo), a PD-1 inhibitor, is a key asset with multiple active indications. Sanofi acquired Translate Bio (mRNA technology) and Kadmon (itepekimab for COPD and pediatric asthma) and has early programs in mRNA therapeutics for cancer and infectious disease. The Rare Diseases unit — historically Genzyme — is a global leader in enzyme replacement therapy for lysosomal storage disorders.

Sanofi Pasteur, the company's vaccine division, is one of the world's largest vaccine producers, with approved vaccines for influenza, dengue, meningococcal disease, typhoid, rabies, and others, and active clinical trials in RSV, mRNA influenza, and pandemic preparedness. Sanofi conducts clinical research through partnerships with NIH, BARDA, CEPI, and academic institutions globally, and runs one of the most active Phase 3 trial programs in the rare disease space.

Frequently Asked Questions — Sanofi

What rare disease trials does Sanofi's Genzyme division sponsor?
Sanofi Genzyme, acquired in 2011, is the rare disease and specialty care unit. Genzyme pioneered enzyme replacement therapy (ERT) for lysosomal storage disorders and continues to run active trials in Gaucher disease (eliglustat, new formulations), Fabry disease (migalastat, pegunigalsidase alfa), Pompe disease (avalglucosidase alfa and next-generation ERTs), and mucopolysaccharidoses. Beyond enzyme replacement, Genzyme has programs in multiple sclerosis, PKD (polycystic kidney disease), and rare neurological conditions. The Genzyme rare disease research network spans centers across North America, Europe, and Latin America, with many trials enrolling patients in pediatric hospitals and metabolic disease centers.
What immunology conditions does Sanofi study in clinical trials?
Sanofi's immunology pipeline is anchored by the dupilumab program (co-developed with Regeneron), covering atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyposis, eosinophilic esophagitis, COPD, and ongoing trials in additional type 2 inflammatory conditions. Beyond dupilumab, Sanofi has itepekimab (Dupixent anti-IL-33 sibling molecule) in late-stage trials for COPD and pediatric asthma, amlitelimab (anti-OX40L) in Phase 3 trials for atopic dermatitis and other inflammatory diseases, and frexalimab (anti-CD40L) in Phase 2 for multiple sclerosis. The breadth of Sanofi's immunology trial activity reflects a strategic decision to become a leading company in type 2 and B-cell-mediated inflammatory diseases.
What COVID-19 and respiratory virus trials does Sanofi run?
Sanofi partnered with GlaxoSmithKline to develop a COVID-19 recombinant protein subunit vaccine (VAT00002/Vidprevtyn Beta) that received EMA authorization. Sanofi Pasteur conducts active trials on quadrivalent influenza vaccines (including high-dose and adjuvanted formulations for older adults), RSV (respiratory syncytial virus) vaccine candidates in older adults and maternal programs, and mRNA-based influenza vaccine candidates leveraging the Translate Bio platform. The company also has active trials in dengue — Dengvaxia outcomes and safety surveillance studies — and investigational vaccines for other flaviviruses.

Clinical Trials by Sanofi

NCT05734521
Recruiting

Avalglucosidase Alfa Pregnancy Study

Pompe Disease
NCT07556159
Recruiting

A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

Asthma
NCT07457580
Recruiting

Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)

Type 1 Diabetes
NCT07247188 Phase 3
Recruiting

Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease

Sickle Cell Disease
NCT06671587 Phase 4
Recruiting

iGlarLixi CGM Study in Chinese T2D Individuals After OADs

Type 2 Diabetes (T2D)
NCT06500702 Phase 2
Recruiting

A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease

Focal Segmental Glomerulosclerosis
NCT06914908 Phase 2
Recruiting

Long-term Safety and Efficacy Evaluation of Lunsekimig in Adult Participants With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) Who Completed a Previous Lunsekimig CRSwNP Study

Chronic Rhinosinusitis With Nasal Polyps
NCT06867094 Phase 2
Recruiting

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

Colitis Ulcerative
NCT06958536 Phase 2
Recruiting

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

Crohn's Disease
NCT07038473
Recruiting

Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)

Type 1 Diabetes
NCT07086976 Phase 3
Recruiting

A Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Oral Rilzabrutinib Compared With Placebo in Participants 18 Years of Age and Older With Warm Autoimmune Hemolytic Anemia

Autoimmune Haemolytic Anaemia
NCT06356571 Phase 2
Recruiting

A Study to Investigate Subcutaneous Isatuximab in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

Plasma Cell Myeloma Refractory
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology