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Recruiting NCT05734521

Avalglucosidase Alfa Pregnancy Study

Trial Parameters

Condition Pompe Disease
Sponsor Sanofi
Study Type OBSERVATIONAL
Phase N/A
Enrollment 100
Sex FEMALE
Min Age N/A
Max Age N/A
Start Date 2022-10-26
Completion 2032-10-31
Interventions
avalglucosidase alfa-NGPT (GZ402666) IVavalglucosidase alfa-NGPT (GZ402666)

Brief Summary

This is a worldwide, descriptive safety study collecting data on women and their offspring exposed to avalglucosidase alfa during pregnancy and/or lactation, to assess the risks of avalglucsodiase alfa on pregnancy and maternal complications and adverse effects in the developing fetus, neonate, and infant. * Outcomes in exposed infants, including growth and development, will be assessed through at least the first year of life. * Data will be collected for approximately 10 years.

Eligibility Criteria

Inclusion Criteria: * Women and their offspring exposed to avalglucosidase alfa during pregnancy and/or lactation for whom an Individual Case Safety Report (ICSR) has been submitted to the Sanofi Global Pharmacovigilance (PV) department, and/or, * Women exposed to avalglucosidase alfa during pregnancy and/or lactation who have provided informed consent to enroll in the Pompe Pregnancy Sub-registry. Exclusion Criteria: There are no exclusion criteria in this study. The above information is not intended to contain all considerations relevant to a potential participation in a clinical trial.

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