Medical Condition

type 1 diabetes

Total Trials

22

Recruiting Now

22

Trial Phases

Phase 2, Phase 1, Phase 2

Diabetes clinical trials span both type 1 (autoimmune beta-cell destruction) and type 2 (insulin resistance) disease, with growing focus on the overlapping spectrum including latent autoimmune diabetes in adults (LADA) and monogenic forms. Research priorities include beta-cell preservation in newly diagnosed type 1 patients, weight-loss-independent glucose control, and prevention of cardiovascular and renal complications.

Current trials evaluate GLP-1/GIP dual agonists (tirzepatide analogs), oral insulin formulations, closed-loop artificial pancreas systems, immunotherapy for type 1 delay, SGLT2 inhibitors in non-diabetic heart failure, and stem-cell-derived islet transplantation. Lifestyle intervention trials also remain an active category.

Many trials separate type 1 and type 2 cohorts; baseline HbA1c, duration of disease, and eGFR are common eligibility criteria.

Frequently Asked Questions — type 1 diabetes Clinical Trials

How many clinical trials are currently recruiting for type 1 diabetes?

ClinicalMetric currently tracks 22 actively recruiting clinical trials for type 1 diabetes, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 22. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for type 1 diabetes?

type 1 diabetes research spans Phase 1 (2 trials), Phase 2 (4 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a type 1 diabetes clinical trial?

Eligibility criteria for type 1 diabetes trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Top Sponsors

Sanofi 2 trials

McGill University 2 trials

Lille University 1 trial

Emily K. Sims 1 trial

Heba M. Ismail 1 trial

type 1 diabetes

Frequently Asked Questions — type 1 diabetes Clinical Trials

Recruiting Clinical Trials

Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes

TArgeting Type 1 Diabetes Using POLyamines (TADPOL)

The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

The T1D Exchange Registry

Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)

Prevalence of NAFLD in T1DM Patients

General Population Level Estimation for Type 1 Diabetes Risk in Children During Routine Care Delivery

A Study Comparing Dexcom Continuous Glucose Monitoring to Point of Care Glucose Testing for the Management of Hospital and Post-Discharge Subjects With Type 1 Diabetes

Screening Program for Type 1 Diabetes in a High-Risk Population

Liom Non-invasive Continuous Glucose Monitor "Clinical Demo" (niCGM)

Discovery Diabetes

Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression

Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes

Microbiome in the Acute Stage of New Onset Paediatric Type 1 Diabetes

Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)

Denosumab for Type 1 Diabetes

The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 Diabetes

Implementation of Support in the Care of Adults Living With Type 1 Diabetes

Omnipod-5 A French Prospective Multicentric Study in Real World (Optimal-B)

Exercise and the Menstrual Cycle in Type 1 Diabetes

Vascular Complications in Children From T1D Diagnosis

Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes