SPONSOR

Johns Hopkins University

Total Trials

Recruiting

Phases

Phase 1, Phase 3, Phase 4, Phase 2, EARLY_Phase 1, Phase 2, Phase 3

Conditions studied: Bilateral Vestibular Hypofunction Bilateral Vestibular Deficiency Bilateral Vestibulopathy Gentamicin Ototoxicity Aminoglycoside Toxicity Vestibular Diseases Sensation Disorders Labyrinth Diseases Other Disorders of Vestibular Function Hypertension

Johns Hopkins University is one of the premier academic medical research institutions in the United States and globally, consistently ranked among the top NIH-funded institutions. The Johns Hopkins School of Medicine and the Bloomberg School of Public Health together support one of the most diverse clinical trial portfolios in US academic medicine, spanning infectious disease, oncology, cardiology, neurology, psychiatry, ophthalmology, and population health. Johns Hopkins Hospital — one of the nation's oldest and most respected teaching hospitals — serves as the primary trial site for Hopkins-initiated studies.

Hopkins has a long tradition of trial leadership in HIV/AIDS (through the Bloomberg School's International Health division and the Baltimore cohort studies), cancer (through the Johns Hopkins Kimmel Cancer Center, an NCI-designated comprehensive cancer center), and cardiovascular disease (through the Ciccarone Center for the Prevention of Cardiovascular Disease). Hopkins investigators have led landmark studies including the Physicians' Health Study, the SPRINT blood pressure trial, and pivotal work on HPV vaccine efficacy in partnership with the NCI.

Johns Hopkins also serves as a primary site for global health trials — particularly in low- and middle-income countries — in tuberculosis, malaria, neonatal health, and maternal nutrition. The Johns Hopkins Center for Clinical Trials is a federally designated Clinical and Translational Science Award (CTSA) hub, providing infrastructure, biostatistics support, and regulatory expertise for more than 400 concurrent investigator-initiated and sponsor-initiated trials across the institution.

Frequently Asked Questions — Johns Hopkins University

What cancer clinical trials does Johns Hopkins University sponsor or lead?

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins is NCI-designated and runs active trials in colorectal cancer (including investigational immunotherapy for mismatch repair-deficient tumors — a breakthrough area pioneered at Hopkins), pancreatic cancer, prostate cancer, brain tumors, leukemia and lymphoma, and lung cancer. Hopkins investigators have led multiple NCI cooperative group trials and have an internationally recognized program in cancer immunoprevention — developing vaccine strategies to prevent cancer in high-risk populations. The institution also conducts first-in-human Phase 1 trials through its Drug Development Core.

Does Johns Hopkins conduct clinical trials for neurological or psychiatric conditions?

Yes. The Johns Hopkins Department of Psychiatry and Behavioral Sciences has an active research program that includes trials on treatment-resistant depression (including psilocybin-assisted therapy — one of the first institutional programs in the US to receive DEA approval for this research), PTSD, addiction medicine (including novel treatments for opioid use disorder), and bipolar disorder. The Department of Neurology runs trials in multiple sclerosis (through the Johns Hopkins MS Center), ALS, Parkinson's disease, and stroke. The Wilmer Eye Institute at Hopkins — one of the top-ranked ophthalmology programs in the world — sponsors trials in macular degeneration, glaucoma, and inherited retinal diseases.

How do patients access Johns Hopkins clinical trials from outside Maryland?

Many Johns Hopkins trials are part of multicenter networks that include enrollment sites at hospitals and clinics nationwide — particularly NCI cooperative group trials conducted through ECOG-ACRIN, the Alliance, or NCI NCTN. For trials that are Hopkins-only, patients often travel to the Johns Hopkins Hospital campus in Baltimore, Maryland. The Hopkins Clinical Research Trials Office (410-502-9100) and the JH clinical trials search engine (trials.hopkinsmedicine.org) can help patients identify open trials and assess eligibility before visiting. Hopkins also offers telehealth pre-screening appointments for some trials.

Johns Hopkins University

Frequently Asked Questions — Johns Hopkins University

Clinical Trials by Johns Hopkins University

Long Term Outcomes After Vestibular Implantation

Groceries Plus Multi-Component Lifestyle Intervention for Adults With Hypertension and Type 2 Diabetes

Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study

Psilocybin and Methylenedioxymethamphetamine (MDMA) for Post-traumatic Stress Disorder (PTSD)

Full-Field Optical Coherence Tomography (FFOCT) for Evaluation of Bronchoscopic Small Biopsy Specimens

Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support

Safe Spaces 4 Sexual Health

e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most

Self-Administered Gaming and Exercise at Home (SAGEH)

Dissemination of the Donor Application: Utilizing Social Media to Identify Potential Live Organ Donors

Shortened Regimen for Drug-susceptible TB in Children

Resilient, Engaged, and Connected Study

The Cancer of the Pancreas Screening-5 CAPS5)Study

Developing a Clinical Outcome Assessment for Opioid Craving

Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)

5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder

Vestibular Implantation in Older Adults

Sleep TO Prevent Post-surgical Pain

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis

Connecting Friends and Health Workers to Boost COVID-19 Vaccination in Latino Communities

1MoreStep: An Intervention to Increase HIV Care Engagement and Reduce Intimate Partner Violence Among Black Women Living With HIV

Dupilumab De-escalation in Pediatric Atopic Dermatitis

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

Scents of Progress: Leveraging a Novel Device for Olfactory Training in Older Adults

Impact of Exogenous Ketones on Breathing in Healthy Volunteers

External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients

Vaporized Cannabis Administration and Co-Administration of Alcohol on Impairment

Vestibular Implantation to Treat Adult-Onset Bilateral Vestibular Hypofunction

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Impact of the Corrie Lipids Digital Health Program on Lipid Optimization

The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Cerebellar Involvement in Cognitive Sequencing

Outcomes of High-risk Non-muscle Invasive Bladder Cancer Treated With Blue Light Resection

Cerebellar Involvement in Alcohol Use Disorder (AUD)

Using Personalized Assessments in the Treatment of Childhood OCD

Group Postpartum and Well-Child Care for Maternal and Infant Health

Registry for Systemic Eczema Treatments

Bedaquiline Roll-out Evidence in Contacts and People Living With HIV to Prevent TB

Clinical Trial Evaluating the Efficacy and Safety of AGB101 for Treatment of Parkinson's Disease Related Psychosis

Dinner Time for Obesity and Prediabetes

Phase 4 of Designed With You