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Recruiting NCT05109429

Developing a Clinical Outcome Assessment for Opioid Craving

Trial Parameters

Condition Opioid Craving
Sponsor Johns Hopkins University
Study Type INTERVENTIONAL
Phase N/A
Enrollment 81
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2022-03-03
Completion 2026-09-30
Interventions
Neutral Cue-induced CravingVisual Opioid Cue-induced CravingVisual and Tactile Opioid Cue-induced Craving

Brief Summary

The purpose of this study is to collect information about opioid craving so that the investigators can develop an opioid craving assessment to improve treatments for individuals with opioid use disorder. To collect this information, the investigators are recruiting individuals in treatment for opioid use disorder who will complete cue-induced opioid craving tasks where these individuals will: (1) look at pictures of neutral objects and touch neutral objects (e.g., water bottles or flashlights), (2) look at opioid-related images, and (3) look and touch opioid-related objects. Participants will then complete a one-on-one interview about the thoughts, feelings and physical sensations the participants experienced during the cue-induced craving session. Participants will also complete questionnaires and existing opioid craving assessments. Finally, participants will provide formal feedback about existing opioid craving assessments with cognitive interviews.

Eligibility Criteria

Inclusion Criteria: * 18 years of age and older * Opioid-positive urine sample at admission visit (excluding individuals receiving Naltrexone). * Current opioid use disorder per Diagnostic Statistical Manual (DSM)-5 * Currently in treatment for opioid use disorder Exclusion Criteria: * Being pregnant or breastfeeding, or may become pregnant during the trial * History of psychosis or mania or other serious psychiatric disorders assessed by the Mini International Neuropsychiatric Interview * Past 30-day suicidal behavior assessed by the Columbia Suicide Severity Rating Scale * Have circumstances that would interfere with study participation (e.g., impending jail). * Positive for illicit substances except opioids and cannabis * Current substance use disorder other than opioid or nicotine * Current intoxication

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