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obesity Clinical Trials in United States

Active clinical trials for obesity with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 33 // Recruiting: 33 Phases: Phase 1, Phase 2, EARLY_Phase 1 // Updated: Daily
Total Trials
33
Recruiting Now
33
Country
🇺🇸 United States

Active Trials in United States (33)

NCT06541509 Phase 1, Phase 2
Recruiting

Mechanisms of Semaglutide Therapy in Heart Failure Patients

Enrollment
10 pts
Country
🇺🇸 United States
University Medical Centre Ljubljana
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NCT05219799 EARLY_Phase 1
Recruiting

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

Enrollment
72 pts
Country
🇺🇸 United States
University of Missouri-Columbia
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NCT07400588 Phase 2
Recruiting

Aleniglipron Phase 2 in Type 2 Diabetes Mellitus

Enrollment
50 pts
Country
🇺🇸 United States
Gasherbrum Bio, Inc., a wholly owne...
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NCT03022682
Recruiting

Inflammation, Diabetes, Ethnicity and Obesity Cohort

Enrollment
350 pts
Country
🇺🇸 United States
University of California, San Franc...
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NCT06571474
Recruiting

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)

Enrollment
60 pts
Country
🇺🇸 United States
Bettina Mittendorfer
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NCT06049420
Recruiting

Lifestyle Medicine: Establishing Clinical Approaches to Chronic Disease for Rural Patients

Enrollment
95 pts
Country
🇺🇸 United States
West Virginia School of Osteopathic...
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NCT04328337 Phase 1, Phase 2
Recruiting

Investigating Whether Acute Elevation of Fatty Acid Levels Alters Cerebral Glucose Transport and Metabolism

Enrollment
40 pts
Country
🇺🇸 United States
University of North Carolina, Chape...
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NCT05950282
Recruiting

Fasting Insulin and HOMA-IR by Age, Sex, Race/Ethnicity, BMI, and PCOS Diagnosis

Enrollment
500 pts
Country
🇺🇸 United States
Lilli Health
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NCT06991296
Recruiting

Concentration of n-3 PUFA Monohydroxylated Derivatives in Adults With Obesity After n-3 PUFA Supplementation.

Enrollment
33 pts
Country
🇺🇸 United States
University of North Carolina, Chape...
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NCT06286761
Recruiting

Routine Validation and Reproducibility Testing of Laboratory Measures and Research Techniques Used for Metabolism Research (VAL)

Enrollment
100 pts
Country
🇺🇸 United States
Bettina Mittendorfer
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NCT07115069
Recruiting

Comparison of Body Composition Changes With Weight Loss Interventions

Enrollment
60 pts
Country
🇺🇸 United States
Vanderbilt University Medical Cente...
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NCT06169137
Recruiting

Pilot Study of Isocaloric Time Restricted Eating on Ketone Metabolism and Immunoregulation

Enrollment
150 pts
Country
🇺🇸 United States
National Institute of Diabetes and ...
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NCT07037433 Phase 3
Recruiting

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

Enrollment
12,800 pts
Country
🇺🇸 United States
Amgen
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NCT07225686 Phase 3
Recruiting

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

Enrollment
250 pts
Country
🇺🇸 United States
Amgen
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NCT06105931 Phase 1
Recruiting

Physiologic Markers of Cardiometabolic Risk in People With Type 1 Diabetes

Enrollment
15 pts
Country
🇺🇸 United States
Yale University
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NCT06972459 Phase 3
Recruiting

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and at Least One Weight-Related Comorbidity

Enrollment
600 pts
Country
🇺🇸 United States
Eli Lilly and Company
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NCT06795386
Recruiting

Chronic Widespread Pain After Rapid Weight Loss in Non-Hispanic Black and Hispanic/Latino/a/x Adults

Enrollment
60 pts
Country
🇺🇸 United States
New York University
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NCT07213466 Phase 4
Recruiting

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

Enrollment
100 pts
Country
🇺🇸 United States
Mayo Clinic
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NCT06151145
Recruiting

Stepped Care for Weight Loss Maintenance

Enrollment
180 pts
Country
🇺🇸 United States
Johns Hopkins University
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NCT06030362
Recruiting

Probiotic Intervention Study

Enrollment
100 pts
Country
🇺🇸 United States
University of California, Los Angel...
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NCT05028205
Recruiting

EBT Fruit and Vegetable Prescription

Enrollment
30 pts
Country
🇺🇸 United States
The University of Tennessee, Knoxvi...
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NCT03947697
Recruiting

Improving Glycemic Control With Electrical Stimulation

Enrollment
60 pts
Country
🇺🇸 United States
University of Texas, El Paso
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NCT05268042
Recruiting

Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents

Enrollment
80 pts
Country
🇺🇸 United States
University of Alabama at Birmingham
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NCT05746039 Phase 1, Phase 2
Recruiting

Feasibility of Semaglutide in Advanced Lung Disease

Enrollment
8 pts
Country
🇺🇸 United States
University of Pennsylvania
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NCT06412536
Recruiting

Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility

Enrollment
10,000 pts
Country
🇺🇸 United States
Brooklyn Clinical Research
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NCT05459636
Recruiting

Inspiratory Muscle Strength Training in Adults With Obesity

Enrollment
44 pts
Country
🇺🇸 United States
Florida State University
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NCT05216042
Recruiting

GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study

Enrollment
200 pts
Country
🇺🇸 United States
University of Alabama at Birmingham
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NCT05326477
Recruiting

Predictors of Behavioral Obesity Treatment Outcomes

Enrollment
230 pts
Country
🇺🇸 United States
Rush University Medical Center
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NCT06445413
Recruiting

Tai Chi as a Novel Strategy to Increase Physical Activity Among Adults Pursuing Metabolic and Bariatric Surgery

Enrollment
24 pts
Country
🇺🇸 United States
Hartford Hospital
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NCT05880758
Recruiting

Impact of Yo-Yo Sleep on Cardiometabolic Health

Enrollment
72 pts
Country
🇺🇸 United States
Columbia University
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NCT05770570 Phase 2
Recruiting

Taxi ROADmAP (Realizing Optimization Around Diet And Physical Activity)

Enrollment
1,785 pts
Country
🇺🇸 United States
Memorial Sloan Kettering Cancer Cen...
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NCT06891352
Recruiting

Optimization of Chrononutrition to Reduce the Risk of Disease in Shift Workers

Enrollment
180 pts
Country
🇺🇸 United States
Salk Institute for Biological Studi...
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NCT05449496
Recruiting

Dietary Intervention to Improve Kidney Transplant Outcomes

Enrollment
120 pts
Country
🇺🇸 United States
University of California, Davis
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Frequently Asked Questions

How many obesity clinical trials are active in United States?
There are currently 33 active clinical trials for obesity with sites in United States, of which 33 are actively recruiting patients.
How can I join a obesity clinical trial in United States?
To join a obesity clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are obesity trials in United States?
Active obesity trials in United States span Phase 1, Phase 2, EARLY_Phase 1, Phase 2, Phase 3, Phase 1, Phase 4. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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