NCT06105164 Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
| NCT ID | NCT06105164 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Brigham and Women's Hospital |
| Condition | Appetitive Behavior |
| Study Type | INTERVENTIONAL |
| Enrollment | 150 participants |
| Start Date | 2024-12-05 |
| Primary Completion | 2029-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 150 participants in total. It began in 2024-12-05 with a primary completion date of 2029-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about the role of the cerebellum in satiety.
Eligibility Criteria
Inclusion Criteria: * Healthy individuals aged 18 to 65 * BMI of 20-35.0 kg/m2 * Normal or corrected-to-normal vision * Good general health * Ability to understand and willingness to sign written informed consent document Exclusion Criteria: * Current and/or past medical conditions * Current and/or past eating disorder * On a restricted diet and/or taking weight loss medication(s) * History of bariatric surgery * Weight fluctuation \>3% in past 3 months * Recent history of illicit recreational drug abuse * Current nicotine use * Intellectual disability * Conditions that might result in increased risks of side effects or complications from TMS or MRI
Contact & Investigator
Laura Holsen, PhD
PRINCIPAL INVESTIGATOR
Brigham and Women's Hospital
Frequently Asked Questions
Who can join the NCT06105164 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Appetitive Behavior. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06105164 currently recruiting?
Yes, NCT06105164 is actively recruiting participants. Contact the research team at lholsen@bwh.harvard.edu for enrollment information.
Where is the NCT06105164 trial being conducted?
This trial is being conducted at Belmont, United States, Boston, United States.
Who is sponsoring the NCT06105164 clinical trial?
NCT06105164 is sponsored by Brigham and Women's Hospital. The principal investigator is Laura Holsen, PhD at Brigham and Women's Hospital. The trial plans to enroll 150 participants.