NCT05326477 Predictors of Behavioral Obesity Treatment Outcomes
| NCT ID | NCT05326477 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Rush University Medical Center |
| Condition | Obesity |
| Study Type | INTERVENTIONAL |
| Enrollment | 230 participants |
| Start Date | 2023-05-26 |
| Primary Completion | 2027-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 230 participants in total. It began in 2023-05-26 with a primary completion date of 2027-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Socioceconomically disadvantaged individuals typically have poor outcomes in behavioral weight loss interventions, but the reasons for this are unknown. This project will characterize the mechanisms through which adverse daily experiences and present bias -- a cognitive adaptation to harsh and unpredictable environments -- account for disparities in weight loss outcomes.
Eligibility Criteria
Inclusion Criteria: 1. Age ≥18 years old 2. Obesity (body mass index ≥30 kg/m2) 3. Meets criteria for either the lower SES or higher SES cohort Exclusion Criteria: 1. Not fluent in English 2. Change in income or financial assets exceeding ±75% of federal poverty guideline within the past 12 months, or expected in the next 6 months, if this change would result in reclassification on SES. 3. Previous or planned bariatric surgery, or concurrent engagement in other behavioral or pharmacological treatment for obesity 4. Resides more than 20 miles away from Rush, or planning to move outside of this geographic area during the study period 5. Body mass index ≥60 kg/m2, due to increased injury risk with exercise 6. History of bariatric surgery, or current engagement in another weight loss therapy 7. Lack of reliable access to cell or landline phone 8. Medical contraindications to treatment, including osteoporosis, cognitive impairment (Montreal Cognitive Assessment ≤25), active substance abuse based on the World Health Organization's ASSIST screener, lack of physician clearance for participation, or serious medical illness (e.g., stage 3 or 4 heart failure, cancer, renal failure, etc.)
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05326477 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05326477 currently recruiting?
Yes, NCT05326477 is actively recruiting participants. Contact the research team at brad_appelhans@rush.edu for enrollment information.
Where is the NCT05326477 trial being conducted?
This trial is being conducted at Chicago, United States.
Who is sponsoring the NCT05326477 clinical trial?
NCT05326477 is sponsored by Rush University Medical Center. The trial plans to enroll 230 participants.
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