NCT06736028 Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity
| NCT ID | NCT06736028 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Alabama at Birmingham |
| Condition | Obesity |
| Study Type | INTERVENTIONAL |
| Enrollment | 20 participants |
| Start Date | 2025-08-01 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 20 participants in total. It began in 2025-08-01 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to investigate whether a Ketogenic Diet (KD) can increase Total Energy Expenditure (TEE), while benefiting appetite, during weight loss maintenance in reduced-obese individuals.
Eligibility Criteria
Inclusion Criteria: * BMI 30-45 kg/m2 * Both men and women * Age between 18-65 years * Sedentary to moderately active (\<2 h/wk of moderate, structured, intentional, exercise) Exclusion Criteria: * Pregnancy or lactation * Daily use of tobacco (\>1 pk/wk) * Change in weight greater than 5 lb in the previous 3 months * Cognitive impairment * Previous bariatric surgery * History of eating disorder * Presence of any condition (e.g. DM2, PCOS, inflammatory disease, untreated thyroid disease, fluid overload states such as chronic kidney disease, congestive heart failure, or cirrhosis) * Use of any medication (e.g., glucocorticoid, GLP-1 analogues, hormone replacement therapy) deemed to interfere with study outcomes. * Pre-menopausal women will need to have a regular menstrual cycle (28+/-2 days) or be on hormonal contraceptives * Fasting glucose plasma concentration \>125 mg/dl and/or HbA1c \> 6.4%
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06736028 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Obesity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06736028 currently recruiting?
Yes, NCT06736028 is actively recruiting participants. Contact the research team at catia197@uab.edu for enrollment information.
Where is the NCT06736028 trial being conducted?
This trial is being conducted at Birmingham, United States.
Who is sponsoring the NCT06736028 clinical trial?
NCT06736028 is sponsored by University of Alabama at Birmingham. The trial plans to enroll 20 participants.
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