Medical Condition

smoking

Total Trials

12

Recruiting Now

12

Trial Phases

Phase 2, Phase 4, Phase 3

ClinicalMetric tracks all active clinical trials for smoking sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — smoking Clinical Trials

How many clinical trials are currently recruiting for smoking?

ClinicalMetric currently tracks 12 actively recruiting clinical trials for smoking, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 12. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for smoking?

smoking research spans Phase 2 (1 trial), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a smoking clinical trial?

Eligibility criteria for smoking trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

Phase 3

Phase 4

Top Sponsors

RAI Services Company 2 trials

University of California, San Francisco 1 trial

University of Florida 1 trial

Children's Hospital of Philadelphia 1 trial

Hospital St. Joseph, Marseille, France 1 trial

Recruiting Clinical Trials

NCT04722835

Recruiting

Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers

University of California, San ...

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NCT07132814

Recruiting

Abuse Liability for Five Modern Oral Nicotine Products

The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence

University of Florida

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NCT07598136

Recruiting

A Study to Determine the Effects of ENDS Flavor Availability on Abstinence Within Smokers

Refer2Quit: Evaluating a Proactive, Tailored, Population Health Approach for Tobacco Treatment for Household Smokers Through a Pediatric Care Network

Children's Hospital of Philade...

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NCT05486455

Recruiting

Evaluation of Lung Cancer CT Screening Performance Among Former and Current Smokers

Hospital St. Joseph, Marseille...

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NCT07089901 Phase 4

Recruiting

Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette Smoking and the Environment

Effect of Different Centrifuge Values on Saliva High Sensitive C-Reactive Protein (Hs-CRP) Levels in Individuals With Different Smoking Amounts

Izmir Katip Celebi University

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NCT05557487

Recruiting

Taiwan Real-world LDCT Screening Behavior and Outcome Research for High Risk Subjects Based on Health Promotion Administration

The Efficacy of Conventional Screening Versus mHealth Screening in Early Detection of Oral Potentially Malignant Disorders and Oral Cancer Amongst the Rural Population of Varanasi: A Prospective and Blinded Study

Memorial Sloan Kettering Cance...

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NCT07312552

Recruiting

Association of Periodontal Status and Smoking With Salivary Inflammasome Markers

Integrating Financial Coaching and Smoking Cessation Coaching

Related Conditions

tobacco use (3) tobacco smoking (2) copd (1) smoking behaviors (1) tobacco (1) smoking cessation (1) second hand tobacco smoke (1) lung cancer (1) high risk cancer (1) pollution exposure (1) family relations (1) smoking cigarette (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology