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Medical Condition

smoking cessation

Total Trials

23

Recruiting Now

23

Trial Phases

Phase 4, Phase 2, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for smoking cessation sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — smoking cessation Clinical Trials

How many clinical trials are currently recruiting for smoking cessation?

ClinicalMetric currently tracks 23 actively recruiting clinical trials for smoking cessation, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 23. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for smoking cessation?

smoking cessation research spans Phase 2 (4 trials), Phase 3 (1 trial), Phase 4 (4 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a smoking cessation clinical trial?

Eligibility criteria for smoking cessation trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

4

Phase 3

1

Phase 4

4

Top Sponsors

University of Wisconsin, Madison 2 trials

Medical University of South Carolina 2 trials

Louisiana State University Health Sciences Center in New Orleans 1 trial

Centre for Addiction and Mental Health 1 trial

Scientific Institute San Raffaele 1 trial

Recruiting Clinical Trials

Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans

Louisiana State University Hea...

NCT05515354 Phase 4

Smoking Cessation and Menstrual Cycle Phase

Centre for Addiction and Menta...

Prevention of Smoking Related Diseases

Scientific Institute San Raffa...

Precision Treatment to Promote Smoking Cessation and Survival in Oncology Patients

Washington University School o...

Metabolism-Informed Care to Aid Alaska Native People to Quit Smoking (QUIT)

Southcentral Foundation

NCT07893158 Phase 2

A Study of Nicotine Orodispersible Tablet on Craving Relief of Male and Female Smoker Volunteers

Implementation of Tobacco Cessation Programming at Community Behavioral Health Sites

University of Chicago

NCT06595459 Phase 4

The Options 2 Study

University of Wisconsin, Madis...

Leveraging Community Pharmacists to Optimize Smoking Cessation Services for Rural Smokers in Appalachia

University of Virginia

NCT06820034 Phase 2, Phase 3

Empowering Cessation ACS South Region

University of Oklahoma

Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches

Medical University of South Ca...

Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments

Medical University of South Ca...

ACT Lung Health Intervention: Phase Two

Dana-Farber Cancer Institute

Trauma-Informed Care for Smoking Cessation for Pregnancy

University of California, San ...

NCT06474299 Phase 4

The Avenues Study: Dual Use Cessation

University of Wisconsin, Madis...

South Africa Smoking Cessation and Engagement in HIV/TB Care Care

Massachusetts General Hospital

Quitxt Mobile Text Messaging Cessation Research Study

The University of Texas Health...

Mindfulness-based Ecological Momentary Intervention for Smoking Cessation Among Cancer Survivors

Rutgers, The State University ...

NCT04783857 Phase 4

Modifying Progesterone and Estradiol Levels to Prevent Postpartum Cigarette Smoking Relapse and Reduce Secondhand Smoke Exposure in Infants and Children

University of Minnesota

Effectiveness of Smoking Cessation Education

Turkey (Türkiye)

Erzurum Technical University

NCT07602699 Phase 2

Multi-Site Trial of Tirzepatide for Smoking Cessation

University of Southern Califor...

NCT05733767 Phase 2

Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study

Baystate Medical Center

Mobile Phone-Based Smoking-Cessation Intervention for Smoking Parents

Beijing Normal University

Related Conditions

smoking (3) smoking cigarette (3) smoking reduction (3) lung cancer screening (2) tobacco use disorder (2) nicotine dependence (2) tobacco smoking (2) nicotine use disorder (2) smoking tobacco (2) smoking behaviors (2) substance use disorders (1) lung cancer (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology