Medical Condition

diabetes

Total Trials

30

Recruiting Now

30

Trial Phases

Phase 1, Phase 2, Phase 3, Phase 4

Diabetes clinical trials span both type 1 (autoimmune beta-cell destruction) and type 2 (insulin resistance) disease, with growing focus on the overlapping spectrum including latent autoimmune diabetes in adults (LADA) and monogenic forms. Research priorities include beta-cell preservation in newly diagnosed type 1 patients, weight-loss-independent glucose control, and prevention of cardiovascular and renal complications.

Current trials evaluate GLP-1/GIP dual agonists (tirzepatide analogs), oral insulin formulations, closed-loop artificial pancreas systems, immunotherapy for type 1 delay, SGLT2 inhibitors in non-diabetic heart failure, and stem-cell-derived islet transplantation. Lifestyle intervention trials also remain an active category.

Many trials separate type 1 and type 2 cohorts; baseline HbA1c, duration of disease, and eGFR are common eligibility criteria.

Frequently Asked Questions — diabetes Clinical Trials

How many clinical trials are currently recruiting for diabetes?

ClinicalMetric currently tracks 30 actively recruiting clinical trials for diabetes, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 30. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for diabetes?

diabetes research spans Phase 1 (2 trials), Phase 2 (1 trial), Phase 3 (1 trial), Phase 4 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a diabetes clinical trial?

Eligibility criteria for diabetes trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Phase 3

Phase 4

Top Sponsors

Fondazione Policlinico Universitario Agostino Gemelli IRCCS 2 trials

Jiangsu HengRui Medicine Co., Ltd. 1 trial

University of Sao Paulo 1 trial

Yufan Wang 1 trial

Eastern Virginia Medical School 1 trial

diabetes

Frequently Asked Questions — diabetes Clinical Trials

Recruiting Clinical Trials

Comparison of HR011408 and NovoRapid® in Subjects With Diabetics

Pleiotropic Effects of Dapagliflozin in Patients With Acute Coronary Syndromes

Optimization and Evaluation of the Diagnosis and Treatment System for Diabetic Retinopathy in Type 2 Diabetes Mellitus

Ultrasound Findings in Diabetic Pregnancies

The T1D Exchange Registry

Taiwan Diabesity Study:Comparison With Mild Obese T2DM Patients Who Under Metabolic Surgery

Comparison of Pitavastatin Plus Ezetimibe Versus High-Intensity Statin Therapy on Risk of New-Onset Diabetes Mellitus

Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial

Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery

Brain Blood Flow and Lactate in Non-obese and Obese Subjects

Leveraging Community-clinical Linkages to Address Unmet Social Needs for People With Diabetes

Evaluating Glial Acetate Metabolism as a Biomarker of Hypoglycemic Counterregulation

Efficacy of Automated Insulin Therapy Early Initiated After Diagnosis on Blood Glucose Control in Children and Adolescents With Type 1 Diabetes

Cognitive Screening and Multidomain Intervention Targeting Cognitive Decline in Type 2 Diabetes (The Brain Care Study)

Telemedicine-Delivered Unified Protocol for Cognitive Behavioral Therapy for Anxiety and Depression

PROtocol of Metabolic and Cryptogenic livEr Disease regisTry for intEgration of Omic Studies

Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RZ-629 in Healthy Subjects and T2D

Achieving Chronic Care equiTy by leVeraging the Telehealth Ecosystem

Wearable Devices Empowering Active Health Initiatives for High-Risk Stroke Populations

Investigating Predictive Factors of Diabetes Occurence After Duodenalpancreatectomy

Cardiometabolic Health in First Time Pregnancy

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Addressing Diabetes by Elevating Access to Nutrition

Role of Adiposomes in Endothelial Dysfunction

Effect of 2-Week Continuous Glucose Monitoring on Glycemic Management in Patients New-to-Insulin on Hospital Discharge

Cardiovascular-Kidney-Metabolic Syndrome in Shanghai Zicitizens

Omnipod-5 A French Prospective Multicentric Study in Real World (Optimal-B)

Diabetes Clinical Decision Support

The EMPA-FIT Study

Metabolic Syndrome and Prediabetes