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periodontitis

Total Trials
16
Recruiting Now
16
Trial Phases
Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for periodontitis sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — periodontitis Clinical Trials

How many clinical trials are currently recruiting for periodontitis?
ClinicalMetric currently tracks 16 actively recruiting clinical trials for periodontitis, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 16. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for periodontitis?
periodontitis research spans Phase 2 (1 trial), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a periodontitis clinical trial?
Eligibility criteria for periodontitis trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
1
Phase 3
1
Top Sponsors
University of Sao Paulo 2 trials
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 2 trials
University of Washington 1 trial
Abant Izzet Baysal University 1 trial
St. Anne's University Hospital Brno, Czech Republic 1 trial

Recruiting Clinical Trials

NCT07424846 Phase 2, Phase 3
Recruiting
Xylitol and the Prevention of Periodontal Disease and Preterm Birth Trial
Enrollment
6,000 pts
Location
Malawi
Sponsor
University of Washington
View Trial →
NCT07551115
Recruiting
Association Between Periodontal Status and the Prevalence of Entamoeba Gingivalis and Trichomonas Tenax
Enrollment
120 pts
Location
Turkey (Türkiye)
Sponsor
Abant Izzet Baysal University
View Trial →
NCT07466966
Recruiting
Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis
Enrollment
106 pts
Location
Czechia
Sponsor
St. Anne's University Hospital...
View Trial →
NCT05088746
Recruiting
Comparing Different Timings for Periodontal Re-evaluation After Non-surgical Periodontal Therapy (NSPT)
Enrollment
52 pts
Location
Italy
Sponsor
University of Parma
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NCT05077618
Recruiting
Nalysis of the Periodontal Microbiota in Elderly Subjects With and Without Alzheimer's Disease: a Case Control Study
Enrollment
94 pts
Location
France
Sponsor
Centre Hospitalier Universitai...
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NCT06428149
Recruiting
Three Types of Papilla Incision in Periodontal Surgery
Enrollment
30 pts
Location
Spain
Sponsor
Universidad de Murcia
View Trial →
NCT07254117
Recruiting
The Role of Granulation Tissue in Periodontal Regeneration
Enrollment
46 pts
Location
Latvia
Sponsor
Riga Stradins University
View Trial →
NCT04719026
Recruiting
PERIODONTAL HEALTH IN PATIENTS ACUTELY ADMITTED FOR MYOCARDIAL INFARCTION: A CASE CONTROL STUDY
Enrollment
320 pts
Location
United Kingdom
Sponsor
University of Aberdeen
View Trial →
NCT06073704
Recruiting
Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients With Obesity
Enrollment
24 pts
Location
Brazil
Sponsor
University of Sao Paulo
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NCT07522684
Recruiting
Polynucleotide + Hyaluronic Acid Gel With Xenogeneic Graft for Intrabony Periodontal Defects
Enrollment
66 pts
Location
Brazil
Sponsor
University of Sao Paulo
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NCT07549347
Recruiting
Is Professional Tooth Cleaning Necessary for Managing Gingivitis (Gingival Inflammation) if Subjects Use Intelligent Toothbrushes?
Enrollment
92 pts
Location
China
Sponsor
Shanghai Ninth People's Hospit...
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NCT07327658
Recruiting
Changes in Periodontal Pocket Depth After Periodontal Treatment
Enrollment
50 pts
Location
Turkey (Türkiye)
Sponsor
Necmettin Erbakan University
View Trial →
NCT06755372
Recruiting
The Role of Toll-like Receptor-4 in Periodontitis Patients With End-stage Renal Disease in a Sample of Egyptian Population
Enrollment
100 pts
Location
Egypt
Sponsor
Ain Shams University
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NCT07293481
Recruiting
Discovery and Validation of Periodontitis Biomarkers
Enrollment
228 pts
Location
China
Sponsor
Shanghai Ninth People's Hospit...
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NCT07312552
Recruiting
Association of Periodontal Status and Smoking With Salivary Inflammasome Markers
Enrollment
116 pts
Location
Turkey (Türkiye)
Sponsor
Uskudar University
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NCT07292870
Recruiting
Biologicals in Management of Intra-Bony Defects
Enrollment
30 pts
Location
Belgium
Sponsor
Universitaire Ziekenhuizen KU ...
View Trial →

Related Conditions

gingivitis (2) periodontal pocket (2) periodontal diseases (2) periodontal disease (2) preterm birth (1) low birthweight neonate (1) developmental delay (1) gingivitis and periodontal diseases (1) peri implantitis (1) non surgical periodontal therapy (1) alzheimer disease (1) periodontal bone loss (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology