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Medical Condition
osteoarthritis knee
Total Trials
11
Recruiting Now
11
Trial Phases
Phase 4
ClinicalMetric tracks all active clinical trials for osteoarthritis knee sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.
Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.
Frequently Asked Questions — osteoarthritis knee Clinical Trials
How many clinical trials are currently recruiting for osteoarthritis knee?
ClinicalMetric currently tracks 11 actively recruiting clinical trials for osteoarthritis knee, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 11. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for osteoarthritis knee?
osteoarthritis knee research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a osteoarthritis knee clinical trial?
Eligibility criteria for osteoarthritis knee trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4 1
Top Sponsors
3 trials
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT06080347
Recruiting
Effect of Anti-inflammatory Diet in Osteoarthritis
Enrollment
72 pts
Location
United States
Sponsor
University of California, San ...
NCT06208631
Recruiting
Effects of Movement Retraining on Knee Loading in Individuals With Knee Osteoarthritis
Enrollment
31 pts
Location
United States
Sponsor
Stanford University
NCT06744036
Recruiting
Effects of Including Interferential Current in a Therapeutic Exercise Program in Individuals With Knee Osteoarthritis
Enrollment
138 pts
Location
Brazil
Sponsor
University of Nove de Julho
NCT06184451
Recruiting
Effects of TENS During the Performance of a Therapeutic Exercise Protocol in Individuals With Knee Osteoarthritis.
Enrollment
90 pts
Location
Brazil
Sponsor
University of Nove de Julho
NCT06054633
Recruiting
L-arginine for Knee Osteoarthritis Patients
Enrollment
340 pts
Location
China
Sponsor
Xiangya Hospital of Central So...
NCT03869996
Recruiting
Total Knee Arthroplasty: Fast Track Protocol is the Future?
Enrollment
64 pts
Location
Italy
Sponsor
Istituto Ortopedico Rizzoli
NCT06466850
Recruiting
Mesenchymal Stem Cells Derived Exosomes in Osteoarthritis Patients
Enrollment
20 pts
Location
Iran
Sponsor
Isfahan University of Medical ...
NCT04364334
Recruiting
Knee Registry (Knieregister)
Enrollment
1,000,000 pts
Location
Netherlands
Sponsor
UMC Utrecht
NCT06856356
Recruiting
Clinical Efficacy and Safety of Robot-assisted Total Knee Arthroplasty
Enrollment
40 pts
Location
China
Sponsor
The First Affiliated Hospital ...
NCT06187038
Recruiting
Effects of Including a Chronic Pain Neuroscience Education Program for Individuals With Knee OA
Enrollment
92 pts
Location
Brazil
Sponsor
University of Nove de Julho
NCT06557018 Phase 4
Recruiting
Efficacy and Safety of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty
Enrollment
60 pts
Location
China
Sponsor
Dezhou Hospital Qilu Hospital ...
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology