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osteoarthritis knee

Total Trials
11
Recruiting Now
11
Trial Phases
Phase 3

ClinicalMetric tracks all active clinical trials for osteoarthritis knee sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — osteoarthritis knee Clinical Trials

How many clinical trials are currently recruiting for osteoarthritis knee?
ClinicalMetric currently tracks 11 actively recruiting clinical trials for osteoarthritis knee, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 11. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for osteoarthritis knee?
osteoarthritis knee research spans Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a osteoarthritis knee clinical trial?
Eligibility criteria for osteoarthritis knee trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 3
1
Top Sponsors
Palo Alto Veterans Institute for Research 1 trial
Istituto Ortopedico Rizzoli 1 trial
Golden Jubilee National Hospital 1 trial
Xiangya Hospital of Central South University 1 trial
Yonsei University 1 trial

Recruiting Clinical Trials

NCT05700682
Recruiting
Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee
Enrollment
120 pts
Location
United States
Sponsor
Palo Alto Veterans Institute f...
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NCT03869996
Recruiting
Total Knee Arthroplasty: Fast Track Protocol is the Future?
Enrollment
64 pts
Location
Italy
Sponsor
Istituto Ortopedico Rizzoli
View Trial →
NCT07551856
Recruiting
Manual Arthroplasty Versus VELYS Robotic-Assisted Solution Functional Alignment Arthroplasty for Knee Osteoarthritis
Enrollment
346 pts
Location
United Kingdom
Sponsor
Golden Jubilee National Hospit...
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NCT06054633
Recruiting
L-arginine for Knee Osteoarthritis Patients
Enrollment
340 pts
Location
China
Sponsor
Xiangya Hospital of Central So...
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NCT07898501
Recruiting
SVF Cellular Composition, Secretome, and Responses in Knee Osteoarthritis
Enrollment
20 pts
Location
South Korea
Sponsor
Yonsei University
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NCT07134244
Recruiting
Development of Computational Models to Predict the Short-, Medium- and Long-term Cartilage Degeneration and Pain for Patients With Early-stage Osteoarthritis or Anterior Cruciate Ligament Injury
Enrollment
105 pts
Location
Denmark
Sponsor
Aalborg University
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NCT06129214
Recruiting
Partial Synovectomy in Articular Side of Quadriceps Tendon Verified to Reduce Crepitus in Retrospective Study
Enrollment
78 pts
Location
South Korea
Sponsor
Gangnam Severance Hospital
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NCT05936814
Recruiting
Adductor Ratio in Severe Varus Gonarthrosis
Enrollment
68 pts
Location
Turkey (Türkiye)
Sponsor
Saglik Bilimleri Universitesi
View Trial →
NCT04364334
Recruiting
Knee Registry (Knieregister)
Enrollment
1,000,000 pts
Location
Netherlands
Sponsor
UMC Utrecht
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NCT04247672
Recruiting
The ATtune Knee Outcome Study
Enrollment
900 pts
Location
Netherlands
Sponsor
Spaarne Gasthuis
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NCT06578182 Phase 3
Recruiting
The Effect of ColcHicine on the Incidence of Knee or Hip Replacements
Enrollment
1,410 pts
Location
Netherlands
Sponsor
Sint Maartenskliniek
View Trial →

Related Conditions

osteoarthritis hip (2) knee osteoarthritis (2) osteo arthritis shoulders (1) synovitis of knee (1) synovitis tenosynovitis hip (1) synovitis (1) pain chronic (1) arthropathy of knee (1) osteo arthritis of the knee (1) osteo arthritis (1) osteoarthritis oa (1) osteoarthritis (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology