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osteoarthritis knee

Total Trials
12
Recruiting Now
12
Trial Phases
Phase 2, Phase 1, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for osteoarthritis knee sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — osteoarthritis knee Clinical Trials

How many clinical trials are currently recruiting for osteoarthritis knee?
ClinicalMetric currently tracks 12 actively recruiting clinical trials for osteoarthritis knee, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 12. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for osteoarthritis knee?
osteoarthritis knee research spans Phase 1 (1 trial), Phase 2 (3 trials), Phase 3 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a osteoarthritis knee clinical trial?
Eligibility criteria for osteoarthritis knee trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
3
Phase 3
2
Top Sponsors
Istituto Ortopedico Rizzoli 2 trials
Wake Forest University 1 trial
Moximed 1 trial
University of Colorado, Denver 1 trial
Brigham and Women's Hospital 1 trial

Recruiting Clinical Trials

NCT05946044
Recruiting
The Osteoarthritis Prevention Study
Enrollment
1,230 pts
Location
United States, Austr...
Sponsor
Wake Forest University
View Trial →
NCT03869996
Recruiting
Total Knee Arthroplasty: Fast Track Protocol is the Future?
Enrollment
64 pts
Location
Italy
Sponsor
Istituto Ortopedico Rizzoli
View Trial →
NCT06843980
Recruiting
MOTION Clinical Trial
Enrollment
100 pts
Location
United States
Sponsor
Moximed
View Trial →
NCT04137835
Recruiting
Non-invasive Evaluation of Upper and Lower Body Function With Showmotion
Enrollment
60 pts
Location
United States
Sponsor
University of Colorado, Denver
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NCT05840887
Recruiting
Knee Osteotomy Associated With Allograft Meniscus Transplantation
Enrollment
52 pts
Location
Italy
Sponsor
Istituto Ortopedico Rizzoli
View Trial →
NCT06096259 Phase 2
Recruiting
Preventing Injured Knees From osteoArthritis: Severity Outcomes
Enrollment
512 pts
Location
United States
Sponsor
Brigham and Women's Hospital
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NCT06414473 Phase 1, Phase 2
Recruiting
CBD for Knee Osteoarthritis
Enrollment
30 pts
Location
United States
Sponsor
University of Florida
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NCT06184451
Recruiting
Effects of TENS During the Performance of a Therapeutic Exercise Protocol in Individuals With Knee Osteoarthritis.
Enrollment
90 pts
Location
Brazil
Sponsor
University of Nove de Julho
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NCT06578182 Phase 3
Recruiting
The Effect of ColcHicine on the Incidence of Knee or Hip Replacements
Enrollment
1,410 pts
Location
Netherlands
Sponsor
Sint Maartenskliniek
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NCT03048201
Recruiting
Physica System Total Knee Replacement Registry Study
Enrollment
800 pts
Location
United States
Sponsor
Limacorporate S.p.a
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NCT05517434 Phase 2, Phase 3
Recruiting
Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA
Enrollment
148 pts
Location
Canada
Sponsor
University Health Network, Tor...
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NCT04230616
Recruiting
Efficacy and Safety of NAVIO
Enrollment
180 pts
Location
Belgium
Sponsor
Sint-Trudo Hospital
View Trial →

Related Conditions

osteoarthritis hip (2) arthropathy of knee (1) osteoarthritis spine (1) malalignment bone (1) post traumatic osteoarthritis (1) acl tear (1) traumatic arthritis (1) avascular necrosis (1) degenerative joint disease of knee (1) rheumatoid arthritis (1) deformity of knee (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology