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Recruiting NCT04247672

NCT04247672 The ATtune Knee Outcome Study

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Clinical Trial Summary
NCT ID NCT04247672
Status Recruiting
Phase
Sponsor Spaarne Gasthuis
Condition Osteoarthritis, Knee
Study Type OBSERVATIONAL
Enrollment 900 participants
Start Date 2020-02-03
Primary Completion 2024-01-22

Eligibility & Interventions

Sex All sexes
Min Age 21 Years
Max Age 90 Years
Study Type OBSERVATIONAL
Interventions
Total Knee Arthroplasty (uncemented rotating platform ATTUNE)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 900 participants in total. It began in 2020-02-03 with a primary completion date of 2024-01-22.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

To accomodate dissatisfied patients with a total knee arthroplasty (TKA) and improve outcomes, several knee systems have been developed. The cemented ATTUNE TKA shows superiority over other established knee systems at short-term, abating with longer follow-up. There have been no studies reporting on the results of the uncemented version of the ATTUNE. Therefore, the main objective of the current study was to report patient reported outcome measures (PROMs), survivorship and complications associated with the uncemented ATTUNE TKA.

Eligibility Criteria

Inclusion Criteria: * End-stage osteoarthritis of the knee warranting joint replacement therapy. * Indicated for an ATTUNE total knee system as part of regular clinical practice. * Capability and willingness to sign informed consent and comply with follow-up procedures. * Capable enough in Dutch or English to be able to understand study procedures Exclusion Criteria: * Unable or unwilling to sign informed consent and comply with follow-up * Indication for primary revision arthroplasty * Absolute indication for cemented fixation (decreased bone stock/quality of spongiosa)

Frequently Asked Questions

Who can join the NCT04247672 clinical trial?

This trial is open to participants of all sexes, aged 21 Years or older, up to 90 Years, studying Osteoarthritis, Knee. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04247672 currently recruiting?

Yes, NCT04247672 is actively recruiting participants. Visit ClinicalTrials.gov or contact Spaarne Gasthuis to inquire about joining.

Where is the NCT04247672 trial being conducted?

This trial is being conducted at Hoofddorp, Netherlands.

Who is sponsoring the NCT04247672 clinical trial?

NCT04247672 is sponsored by Spaarne Gasthuis. The trial plans to enroll 900 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology