Medical Condition

knee osteoarthritis

Total Trials

37

Recruiting Now

37

Trial Phases

Phase 2, Phase 4

ClinicalMetric tracks all active clinical trials for knee osteoarthritis sourced from ClinicalTrials.gov. Each listing includes the NCT identifier, current recruitment status, phase, primary endpoints, sponsor, estimated enrollment, and participating countries — updated daily as new studies open and status changes.

Recruiting trials currently enrolling participants, with eligibility criteria and age requirements
Phase 1–4 studies from early safety trials to post-marketing surveillance
NIH, pharmaceutical sponsor, and academic medical center studies worldwide
AI-powered plain-language summary available for every trial listing

Frequently Asked Questions — knee osteoarthritis Clinical Trials

How many clinical trials are currently recruiting for knee osteoarthritis?

ClinicalMetric currently tracks 37 actively recruiting clinical trials for knee osteoarthritis, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 37. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for knee osteoarthritis?

knee osteoarthritis research spans Phase 2 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a knee osteoarthritis clinical trial?

Eligibility criteria for knee osteoarthritis trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

Phase 4

Top Sponsors

Riphah International University 4 trials

Istituto Ortopedico Rizzoli 2 trials

CEN Biotech 1 trial

Rush University Medical Center 1 trial

I.M. Sechenov First Moscow State Medical University 1 trial

knee osteoarthritis

Frequently Asked Questions — knee osteoarthritis Clinical Trials

Recruiting Clinical Trials

Knee Osteoarthritis and Thermal Spa Treatment

Comparison of INIT and Dry Needling on Trigger Points in Knee OA

Bowen Technique With Retro-walking on Hamstring Flexibility in Knee Osteoarthritis

Effects of Voodoo Flossing Technique in Knee Osteoarthritis Patients

ROAM OA: Functional and Patient Reported Outcomes Wearing a Knee Brace for Unicompartmental OA

Total Knee Arthroplasty in Varus Deformity

Pulsed Radiofrequency Therapy vs Canal Adductor Blockade in Knee Osteoarthritis

Genicular Artery Embolisation for Knee Osteoarthritis II

Effects of a Yoga Program on the Functionality of Individuals

Evaluating XPERIENCE™ Advanced Surgical Irrigation

Comparison of Effect of Virtual Reality and Kinetic Chain Exercises in Knee Osteoarthritis

The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction.

Crosscultural Adaptation And Validation Of The Italian Version Of The New Knee Society Knee Scoring System

Somatosensory Amplification and Psychological and Functional Status In Patients With Knee Osteoarthritis

Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

Genicular Artery Embolization for Reducing Pain in Medically Refractory Symptomatic Knee Osteoarthritis

Innovations in Genicular Outcomes Registry

Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty

The Effect of Hybrid Tele-rehabilitation Versus In Person Rehabilitation on Pain and Function in Patients With Knee Osteoarthritis

Effect of Foot Massage on Pain and Analgesic Consumption in Total Knee Prosthesis

Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis

Perineural Dextrose Versus Local Anesthetic Injections in Knee Osteoarthritis

Comparison of the Effect of Genicular Nerve Block and Physical Therapy in Patients With Knee Osteoarthritis

Magnetic Field Therapy Versus Transcutaneous Electrical Nerve-stimulation in Knee Osteoarthritis

Gait Analysis of a Lateral-Pivot Design Total Knee Replacement

Development of an Outcome Score for Patients With Knee Osteoarthritis and Knee Joint Endoprosthesis Using an App

Homologus PRP in the Infiltrative Treatment of Knee Osteoarthritis in Young Athletic Patients

Adapting Rehabilitation Delivery for Maximum Impact at Home-2 (ReDI-2)

Aerobic Vs Neuromuscular Exercise for Knee OA

Move and Snooze: Adding Insomnia Treatment to an Exercise Program to Improve Pain Outcomes in Older Adults With Knee Osteoarthritis

Fluoroscopic Versus Ultrasound Guidance for Cooled Radiofrequency Ablation of Geniculate Nerves in Knee Osteoarthritis: A Randomized Control Trial

Knee Biofeedback Rehabilitation Through Game Therapy

Comparison of Image Based Robotic Total Knee Arthroplasty vs Imageless Augmented Reality Assisted Total Knee Arthroplasty

The Effect of Hyaluronic Acid Injection on TNF-Alpha and IL-1β in Knee Osteoarthritis

Evaluating Changes in Synovial Fluid Before and After GAE for Knee Osteoarthritis

Ischemic Preconditioning in Osteoarthritis and Back Pain

Perineural Prolotherapy in Chronic Knee Osteoarthritis Pain.