NCT07558317 The Effect of Resistance Exercise in Patients With Lower Limb Lymphedema (the LymphEx Study)
| NCT ID | NCT07558317 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Carsten Bogh Juhl |
| Condition | Lymphedema |
| Study Type | INTERVENTIONAL |
| Enrollment | 36 participants |
| Start Date | 2026-05-05 |
| Primary Completion | 2027-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 36 participants in total. It began in 2026-05-05 with a primary completion date of 2027-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The aim of the study is to investigate the short-term (within 2 weeks) effects of resistance exercise with and without compression garments on lower limb lymphedema(LLL). Additionally, the study will explore the immediate response in LLL to resistance exercise (2 hours and 24 hours post-exercise). Participants will continously wear a circumfencential sensor at the calf (CIMON from Icompression) under a compression garment and an activity tracker (SENS Motion from SENS Innovation Aps) at the thigh for 3 periods (two with supervised exercise sessions of 2 weeks and one control period). Participants will attend supervised resistance exercise 2-3 times per week for 2 periods of 2 weeks (one with compression garment and one without). Assessments with the principal investigator will be scheduled before and after every 2 week period. Participants will keep a digital diary or diary in paper of their lymphedema related symptoms and experienced issues with the sensors or app.
Eligibility Criteria
Inclusion Criteria: * verified diagnosis of lymphedema of the lower limb * completed compression bandaging * adherence to compression garment in daytime (minumum 5-6 days per week) * calf circumference \> 35 and \<75 cm Exclusion Criteria: * severe neuropathy of the lower leg * severe skin problems or wounds at the lower leg * cellulitis, DVT or acute injuries of the lower limb \< 2 months prior to inclusion * ongoing adjuvant treatment for cancer
Contact & Investigator
Carsten B Juhl, Professor
STUDY CHAIR
Herlev Gentofte Hospital
Frequently Asked Questions
Who can join the NCT07558317 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Lymphedema. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07558317 currently recruiting?
Yes, NCT07558317 is actively recruiting participants. Contact the research team at merete.celano.wittenkamp@regionh.dk for enrollment information.
Where is the NCT07558317 trial being conducted?
This trial is being conducted at Herlev, Denmark.
Who is sponsoring the NCT07558317 clinical trial?
NCT07558317 is sponsored by Carsten Bogh Juhl. The principal investigator is Carsten B Juhl, Professor at Herlev Gentofte Hospital. The trial plans to enroll 36 participants.