NCT07889856 Use of Reconstructive Microsurgery for the Treatment of Lymphedema
| NCT ID | NCT07889856 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Istituto Ortopedico Rizzoli |
| Condition | Lymphedema |
| Study Type | OBSERVATIONAL |
| Enrollment | 15 participants |
| Start Date | 2026-09-29 |
| Primary Completion | 2027-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 15 participants in total. It began in 2026-09-29 with a primary completion date of 2027-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Lymphedema is a chronic condition characterized by the accumulation of lymphatic fluid in tissues, frequently resulting from oncological treatments, trauma, or cancer. This condition causes significant functional impairment and severely impacts patients' quality of life, requiring complex and multidisciplinary therapeutic approaches. In recent years, reconstructive microsurgery has played an increasingly important role in lymphedema treatment due to high-precision technologies. The use of ultra-high magnification operating microscopes allows the visualization of sub-millimetric vascular structures, enabling lymphatic-venous anastomoses and lymph node transfers on extremely small vessels (0.3-0.5 mm). Additionally, advanced intraoperative imaging, such as indocyanine green fluorescence, allows real-time identification of lymphatic vessels and patency assessment, improving surgical accuracy and clinical outcomes. While recent experience shows high procedural success rates, a retrospective and systematic analysis of clinical data is necessary to structuredly evaluate functional outcomes. Therefore, this retrospective study aims to analyze the clinical experience gained to define the role of advanced microsurgical technologies in optimizing the therapeutic pathway for patients with lymphedema
Eligibility Criteria
Inclusion Criteria: * Age 18 years and older (male and female); * Patients undergoing reconstructive microsurgery with lymphatic-venous anastomosis; * Surgical procedure performed between January 1, 2024, and December 31, 2025; * Minimum follow-up period of 6 months. Exclusion Criteria: • Absence of one or more inclusion criteria.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07889856 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Lymphedema. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07889856 currently recruiting?
Yes, NCT07889856 is actively recruiting participants. Contact the research team at francesco.mori@ior.it for enrollment information.
Where is the NCT07889856 trial being conducted?
This trial is being conducted at Bologna, Italy.
Who is sponsoring the NCT07889856 clinical trial?
NCT07889856 is sponsored by Istituto Ortopedico Rizzoli. The trial plans to enroll 15 participants.