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Medical Condition

autism spectrum disorder

Total Trials

39

Recruiting Now

39

Trial Phases

Phase 2, Phase 1, Phase 2, EARLY_Phase 1

Autism spectrum disorder (ASD) trials target core symptoms (social communication, restricted/repetitive behaviors) as well as co-occurring conditions including anxiety, sleep disturbance, and gastrointestinal problems. The heterogeneity of ASD β€” driven by hundreds of genetic variants β€” has driven interest in genotype-stratified trials that enroll specific genetic subtypes (SHANK3, CHD8, FMR1).

Trials evaluate oxytocin nasal spray, vasopressin receptor modulators, mGluR5 antagonists in fragile X, bumetanide (GABA modulator), transcranial magnetic stimulation, and early intensive behavioral interventions. Biomarkers including EEG connectivity measures and eye-tracking are being validated as objective outcome measures.

Frequently Asked Questions — autism spectrum disorder Clinical Trials

How many clinical trials are currently recruiting for autism spectrum disorder?

ClinicalMetric currently tracks 39 actively recruiting clinical trials for autism spectrum disorder, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 39. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for autism spectrum disorder?

autism spectrum disorder research spans Phase 1 (3 trials), Phase 2 (4 trials), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a autism spectrum disorder clinical trial?

Eligibility criteria for autism spectrum disorder trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

3

Phase 2

4

Phase 4

1

Top Sponsors

Stanford University 5 trials

Children's Hospital Medical Center, Cincinnati 3 trials

Istituto per la Ricerca e l'Innovazione Biomedica 2 trials

Riphah International University 2 trials

Ohio State University 1 trial

Recruiting Clinical Trials

NCT03866668 Phase 2

A Study of Esomeprazole in Children With Autism

Stanford University

Motor-voice Assessment in Infants (MAMI)

Ohio State University

Brain Imaging in Babies Study

King's College London

Emotional Skills Training with Social Robot

Istituto per la Ricerca e l'In...

The Effect of a Multispecies Probiotics on Autism Symptoms in Children

Medical University of Warsaw

ACT Combined Yoga for Parental Burnout in Parents with Autistic Children

Harbin Medical University

Accuracy of Community General Pediatrician Diagnosis of Autism Compared to a Multidisciplinary Team Assessment

Holland Bloorview Kids Rehabil...

Investigating Autimia, a Digital Intervention for Patients With Autism Spectrum Disorder

SQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism

United States, Ukrai...

American Federation of Medical...

COMpassion for Psychiatric Disorders And Self-Stigma

University Hospital, Strasbour...

Patterns of Neurodevelopmental Disorders

Establish the Couple Intervention Program for Adults With Autism Spectrum Disorder

National Taiwan University Hos...

NCT07304440 Phase 1, Phase 2

Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study

Adia Med of Winter Park LLC

Retrieval-Based Word Learning in Autistic Children

Louisiana State University and...

Effects of Muscle Energy Technique With and Without Stationary Cycling on Toe Walking With ASD

Riphah International Universit...

rTMS for Depression in Young Adults With Autism

Centre for Addiction and Menta...

Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children

Stanford University

Evaluating Additive Effects of Including Canines in Regulating Together

Children's Hospital Medical Ce...

Evaluation of Behavioural Psycho & Physiological Responses in People With ASD During a Blood Test in Routine Care Practice

Centre Hospitalier Charles Per...

Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills

Centre Hospitalier St Anne

STRW-T Intervention for Autistic Adolescents in 11th and 12th Grade

Children's Hospital Medical Ce...

Static Balance Assessment in Children With ASD Using VRRS

Istituto per la Ricerca e l'In...

Evaluation of Motor Skills, Balance, Dual Task, and Social Adaptation in Individuals with Autism

Turkey (Türkiye)

Kırıkkale University

SWOC Activities on Balance, Gait and Endurance in Children With Autism Spectrum Disorder

Riphah International Universit...

NCT07432776 EARLY_Phase 1

Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design

Penn State University

NCT05501678 Phase 2

Trial of Diphenhydramine for Sleep in Children With Autism

Stanford University

Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

Healing Hope International

Caregiver Training to Support Children With Social Communication Challenges

Western University, Canada

Physical Activity and Community EmPOWERment Project

University of North Carolina, ...

A Comparison of Two School Based Interventions to Manage Anxiety in Autistic Students

University of Colorado, Denver

Behavior Analytic Support of Needle-related Hospital Visits for Autistic Patients

Boston Medical Center

Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth

Stanford University

Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

Stanford University

NCT04060030 Phase 2

Treatment of Social and Language Deficits With Leucovorin for Young Children With Autism

Southwest Autism Research & Re...

NCT06853665 Phase 4

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

Improving Academic and Social Functioning in Middle-Schoolers With Autism

Children's Hospital Medical Ce...

Promoting Emotional and Autonomic Control Through Guided Breathing Exercises for Emerging Adults With Autism

Universitaire Ziekenhuizen KU ...

Interactive Mirroring Games wIth sOcial Robot (IOGIOCO) and Robotic System Adapted Into a Clinical Scale (RISCALE)

Fondazione Don Carlo Gnocchi E...

NCT06030752 Phase 1

WMT for Autism Spectrum Disorder (ASD)

The Second Hospital of Nanjing...

Related Conditions

autism (10) neurodevelopmental disorders (5) cerebral palsy infantile (2) down syndrome (2) asd (2) autism spectrum disorder asd (2) emotion regulation (2) williams syndrome (2) pre term (1) motor delay (1) attention deficit hyperactivity disorder (1) neurodevelopmental conditions (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology