← Browse by Condition

Medical Condition

autism spectrum disorder

Total Trials

30

Recruiting Now

30

Trial Phases

Phase 2, Phase 3, Phase 4

Autism spectrum disorder (ASD) trials target core symptoms (social communication, restricted/repetitive behaviors) as well as co-occurring conditions including anxiety, sleep disturbance, and gastrointestinal problems. The heterogeneity of ASD β€” driven by hundreds of genetic variants β€” has driven interest in genotype-stratified trials that enroll specific genetic subtypes (SHANK3, CHD8, FMR1).

Trials evaluate oxytocin nasal spray, vasopressin receptor modulators, mGluR5 antagonists in fragile X, bumetanide (GABA modulator), transcranial magnetic stimulation, and early intensive behavioral interventions. Biomarkers including EEG connectivity measures and eye-tracking are being validated as objective outcome measures.

Frequently Asked Questions — autism spectrum disorder Clinical Trials

How many clinical trials are currently recruiting for autism spectrum disorder?

ClinicalMetric currently tracks 30 actively recruiting clinical trials for autism spectrum disorder, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 30. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for autism spectrum disorder?

autism spectrum disorder research spans Phase 2 (1 trial), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a autism spectrum disorder clinical trial?

Eligibility criteria for autism spectrum disorder trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

1

Phase 3

1

Phase 4

1

Top Sponsors

Stanford University 3 trials

Children's Hospital Medical Center, Cincinnati 3 trials

National Taiwan University Hospital 3 trials

Massachusetts General Hospital 2 trials

Riphah International University 2 trials

Recruiting Clinical Trials

Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism

Stanford University

Transcranial Magnetic Stimulation (TMS) Study for Adults With Autism Spectrum Disorder (ASD)

Yale University

Developing Brain, Impulsivity and Compulsivity

National Institute of Mental H...

Application of Virtual Reality Technology to Treatment of Social Anxiety

The University of Texas Health...

The Impact of Sensory Integration on Attention in Autism

Istituto per la Ricerca e l'In...

Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD

Stanford University

Heart Rate Informed Changes in Care for Non-Communicating Patients

University of Oslo

Peer Interventions for Preschoolers With Autism

University of Kansas

Adaptation of the NEAR Cognitive Remediation Method to Child and Adult Autism by Including Social Scenarios and Skills

Centre Hospitalier St Anne

COMpassion for Psychiatric Disorders And Self-Stigma

University Hospital, Strasbour...

Evaluating Additive Effects of Including Canines in Regulating Together

Children's Hospital Medical Ce...

NCT05664789 Phase 2, Phase 3

Targeting the Neurobiology of RRB in Autism Using N-acetylcysteine: Trial

Stanford University

ASD and Habituation to Dental Examination

Oral Health Center of Expertis...

Exploring the Gut-Brain-Behavior Axis With Biomarkers, Probiotic Efficacy, and Artificial Intelligence Algorithms

National Taiwan University Hos...

Flexibility and the Predictive Brain in Autistic Males and Females

University Hospital, Grenoble

Feasibility of a Culturally Adapted Nurse-Led COPE Intervention for Caregivers of Children With Autism Spectrum Disorder

Khyber Medical University Pesh...

Auricular Transcutaneous Electrical Nerve Stimulation Treatment of Autism

Massachusetts General Hospital

Word Learning From Parentese in Autistic Children

The University of Texas at Dal...

FMS-CrossFit Training Program (FCTP) to Improve School Readiness in Preschool Children With Autism Spectrum Disorder

Peking University

Transcranial Direct Current Stimulation in Children With Autism

New York State Institute for B...

Improving Academic and Social Functioning in Middle-Schoolers With Autism

Children's Hospital Medical Ce...

Effects of Muscle Energy Technique With and Without Stationary Cycling on Toe Walking With ASD

Riphah International Universit...

Characterization of Dysmorphology in Subjects With Creatine Transporter Deficiency

Eunice Kennedy Shriver Nationa...

Study Comparing the Effects of SPM Techniques, Individually vs. Grouped in Children With ASD

Riphah International Universit...

The Plasticity of Social Brain Network in Adults With Autism Spectrum Disorder

National Taiwan University Hos...

Social Robots and Board Games for Children With Autism Spectrum Disorder

National Taiwan University Hos...

ADNP Syndrome: The Seaver Autism Center for Research and Treatment is Characterizing ADNP-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

Icahn School of Medicine at Mo...

The Effect of a Multispecies Probiotics on Autism Symptoms in Children

Medical University of Warsaw

Autism Doula Program Evaluation

Children's Hospital Medical Ce...

NCT07439042 Phase 4

Buspirone for Anxiety in Autistic Youth

Massachusetts General Hospital

Related Conditions

autism (5) depression (2) anxiety (2) typical development (1) obsessive compulsive disorder (1) conduct disorder (1) attention deficit hyperactivity disorder (1) social anxiety disorder (1) asperger syndrome (1) intellectual disability (1) communication nonverbal (1) bipolar disorder (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology