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autism spectrum disorder

Total Trials

34

Recruiting Now

34

Trial Phases

Phase 1, Phase 2, Phase 2

Autism spectrum disorder (ASD) trials target core symptoms (social communication, restricted/repetitive behaviors) as well as co-occurring conditions including anxiety, sleep disturbance, and gastrointestinal problems. The heterogeneity of ASD β€” driven by hundreds of genetic variants β€” has driven interest in genotype-stratified trials that enroll specific genetic subtypes (SHANK3, CHD8, FMR1).

Trials evaluate oxytocin nasal spray, vasopressin receptor modulators, mGluR5 antagonists in fragile X, bumetanide (GABA modulator), transcranial magnetic stimulation, and early intensive behavioral interventions. Biomarkers including EEG connectivity measures and eye-tracking are being validated as objective outcome measures.

Frequently Asked Questions — autism spectrum disorder Clinical Trials

How many clinical trials are currently recruiting for autism spectrum disorder?

ClinicalMetric currently tracks 34 actively recruiting clinical trials for autism spectrum disorder, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 34. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for autism spectrum disorder?

autism spectrum disorder research spans Phase 1 (1 trial), Phase 2 (5 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a autism spectrum disorder clinical trial?

Eligibility criteria for autism spectrum disorder trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

1

Phase 2

5

Top Sponsors

Stanford University 3 trials

Chang Gung Memorial Hospital 2 trials

Istituto per la Ricerca e l'Innovazione Biomedica 2 trials

Children's Hospital Medical Center, Cincinnati 2 trials

Dartmouth-Hitchcock Medical Center 1 trial

Recruiting Clinical Trials

TF-CBT for Autistic Youth Pilot Implementation - Open Pilot

Dartmouth-Hitchcock Medical Ce...

Effects of Lactobacillus Plantarum PS128 in Children With ASD

Chang Gung Memorial Hospital

Better Understand Motor Deficits Associated With Autism Spectrum Disorders: Development of an Assessment Protocol

Centre Hospitalier Charles Per...

Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder

Loma Linda University

Online Evaluation of the Diagnostic Accuracy of BlinkLab's Digital Assessments for Autism

Blinklab Limited

Aut-CARE Intervention to Improve Cognitive and Emotional Functioning in Young Adults on the Autism Spectrum

Fundació Institut de Recerca d...

Emotional Skills Training with Social Robot

Istituto per la Ricerca e l'In...

Pai.ACT - An Artificial Intelligence Driven Chatbot Assisted ACT

Chinese University of Hong Kon...

Longitudinal Study of Neurogenetic Disorders

Columbia University

Speech-in-noise Perception in Autism and Fragile X

Children's Hospital Medical Ce...

NCT07304440 Phase 1, Phase 2

Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study

Adia Med of Winter Park LLC

Brain Imaging in Babies Study

King's College London

A Comparison of Two School Based Interventions to Manage Anxiety in Autistic Students

University of Colorado, Denver

Feasibility of a Culturally Adapted Nurse-Led COPE Intervention for Caregivers of Children With Autism Spectrum Disorder

Khyber Medical University Pesh...

Feasibility and Efficacy of rTMS in Depression in Patients With Autism Spectrum Disorder (ASD)

Hospital Center Guillaume Régn...

pBFS Guided rTMS Over Cognitive Control Network for ASD

Changping Laboratory

NCT03866668 Phase 2

A Study of Esomeprazole in Children With Autism

Stanford University

Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)

Hugo W. Moser Research Institu...

A Pilot Study on Efficacy of Digital Therapeutic NDTx-02 for Executive Function in Children and Adolescents With ADHD or ASD

NCT05540574 Phase 2

Trial of Zolpidem for Sleep in Children With Autism

Stanford University

NCT07199218 Phase 2

Placebo-Controlled Study of Terpenes-Enriched Cannabis Oil T1/C28 for Children With Autism

Bazelet Nehushtan LtD.

Social Groups for Autistic Young Adults (SDARIYA)

Drexel University

Improving Social Communication in Individuals With ASD Using AI

Stanford University

NCT06081348 Phase 2

Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders

Holland Bloorview Kids Rehabil...

A Digital Health Parent-Training Intervention for Children With Social Communication Delays

Florida International Universi...

Transcranial Direct Current Stimulation in Children With Autism

New York State Institute for B...

Autism Doula Program Evaluation

Children's Hospital Medical Ce...

Effect of a Casein and Gluten Free Diet in Mexican Children With Autism Spectrum Disorder

University of Guadalajara

Platform for the Prospective Mother-child Study of the Determinants of Neurodevelopmental Disorders

University Hospital, Montpelli...

Early Neurodivergent Developmental Trajectories in Autism and in Response to the ESDM Intervention

Istituto per la Ricerca e l'In...

EEG Microstates Across At-Risk Mental States

Centre Hospitalier St Anne

Play Therapy With Gamified Biofeedback in Children With Autism Spectrum Disorder

Luiz Alexandre Viana Magno

Explore the Impacts of Theta Burst Stimulation Over the Right Inferior Frontal Gyrus in Autism Spectrum Disorder: Combination of Clinical Symptoms, Neuropsychological Function and MRI

Chang Gung Memorial Hospital

Integrated Platform for Measuring and Reducing Symptoms of Autism Spectrum Disorder

State University of New York -...

Related Conditions

autism (8) neurodevelopmental disorders (4) attention deficit hyperactivity disorder (3) autism spectrum disorder asd (2) neurodevelopmental conditions (2) intellectual disability (2) fragile x syndrome (2) anxiety disorders (2) depression (2) anxiety (2) social communication delay (2) ptsd and trauma related symptoms (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: July 2026 · Data Methodology