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Medical Condition

autism

Total Trials

17

Recruiting Now

17

Trial Phases

Phase 2, Phase 3, Phase 1, Phase 2, Phase 1

Autism spectrum disorder (ASD) trials target core symptoms (social communication, restricted/repetitive behaviors) as well as co-occurring conditions including anxiety, sleep disturbance, and gastrointestinal problems. The heterogeneity of ASD β€” driven by hundreds of genetic variants β€” has driven interest in genotype-stratified trials that enroll specific genetic subtypes (SHANK3, CHD8, FMR1).

Trials evaluate oxytocin nasal spray, vasopressin receptor modulators, mGluR5 antagonists in fragile X, bumetanide (GABA modulator), transcranial magnetic stimulation, and early intensive behavioral interventions. Biomarkers including EEG connectivity measures and eye-tracking are being validated as objective outcome measures.

Frequently Asked Questions — autism Clinical Trials

How many clinical trials are currently recruiting for autism?

ClinicalMetric currently tracks 17 actively recruiting clinical trials for autism, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 17. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for autism?

autism research spans Phase 1 (2 trials), Phase 2 (2 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a autism clinical trial?

Eligibility criteria for autism trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

2

Phase 2

2

Phase 3

1

Top Sponsors

University of Pennsylvania 2 trials

Vanderbilt University Medical Center 1 trial

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 1 trial

American University 1 trial

Umeå University 1 trial

Recruiting Clinical Trials

Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

Vanderbilt University Medical ...

NCT07450443 Phase 2, Phase 3

Role of the Gut Vascular Barrier and Microbiota in Autism Spectrum Disorders

Fondazione I.R.C.C.S. Istituto...

Testing a Measurement Feedback App to Improve Data Quality, Supervision & Outcomes in Behavioral Health

University of Pennsylvania

Cerebellum and Autism: Regional Specialization for Social and Executive Functions

American University

Five Digits Test - Validation of a Neuropsychological Test of Inhibition for Patients With Neuropsychiatric Conditions

Umeå University

The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

University of Pittsburgh

Motor Function Assessment and VR-based Motor Training in Adults With Autism Spectrum Disorder

National Taiwan University Hos...

Evaluating Georgia Part C Implementation Outcomes

Emory University

Better Social, Emotional Communication, Healthy Relationship and ASD Accommodation Skills: Emotional Intelligence ("EQ") Training for Autistic People and ASD Accommodation Training for People Who Care

Kairon Connect, PBC

NCT07304440 Phase 1, Phase 2

Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study

Adia Med of Winter Park LLC

NCT07622316 Phase 1

GAIP ASD Research Study

Greater Atlanta Integrative Pe...

Investigating the Impacts of Early Life Experience on the Brain & Behaviour

University of Manchester

Improving Academic and Social Functioning in Middle-Schoolers With Autism

Children's Hospital Medical Ce...

Magnetoencephalography in Children

Children's Hospital of Fudan U...

Speech of Kids After Neonatal Encephalopathy

Semmelweis University

Online Pivotal Response Treatment Training in Autism Spectrum Disorder

Stanford University

Randomized Clinical Trial of TUNE In 3.0: A Social/Emotional Program for Adults With Autism Spectrum Disorder

University of Pennsylvania

Related Conditions

autism spectrum disorder (7) autism spectrum disorder asd (3) adhd (3) asd (2) adhd attention deficit disorder with hyperactivity (2) autism disorder (1) challenging behavior (1) oppositional defiant disorder (1) sleep disturbance (1) communication disorder childhood (1) mental health (1) neurodevelopment (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology