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Medical Condition

autism

Total Trials

20

Recruiting Now

20

Trial Phases

Phase 2, Phase 3, Phase 1, Phase 2

Autism spectrum disorder (ASD) trials target core symptoms (social communication, restricted/repetitive behaviors) as well as co-occurring conditions including anxiety, sleep disturbance, and gastrointestinal problems. The heterogeneity of ASD β€” driven by hundreds of genetic variants β€” has driven interest in genotype-stratified trials that enroll specific genetic subtypes (SHANK3, CHD8, FMR1).

Trials evaluate oxytocin nasal spray, vasopressin receptor modulators, mGluR5 antagonists in fragile X, bumetanide (GABA modulator), transcranial magnetic stimulation, and early intensive behavioral interventions. Biomarkers including EEG connectivity measures and eye-tracking are being validated as objective outcome measures.

Frequently Asked Questions — autism Clinical Trials

How many clinical trials are currently recruiting for autism?

ClinicalMetric currently tracks 20 actively recruiting clinical trials for autism, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 20. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for autism?

autism research spans Phase 1 (1 trial), Phase 2 (4 trials), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a autism clinical trial?

Eligibility criteria for autism trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

1

Phase 2

4

Phase 3

1

Phase 4

1

Top Sponsors

Stanford University 6 trials

National Taiwan University Hospital 2 trials

Istituto per la Ricerca e l'Innovazione Biomedica 2 trials

Sherief Abd-Elsalam 1 trial

Adia Med of Winter Park LLC 1 trial

Recruiting Clinical Trials

NCT03866668 Phase 2

A Study of Esomeprazole in Children With Autism

Stanford University

NCT04766177 Phase 3

Role of Bumetanide in Treatment of Autism

Sherief Abd-Elsalam

NCT07304440 Phase 1, Phase 2

Adia MED of Winter Park LLC Autism Spectrum Disorder Research Study

Adia Med of Winter Park LLC

Assessing Outcomes of Three Different Museum-based Social Prescription Programs in Autistic Adults

National Taiwan University Hos...

Magnetoencephalography in Children

Children's Hospital of Fudan U...

Parent-Mediated Intervention Targeting Insistence on Sameness for Autistic Children

Stanford University

Static Balance Assessment in Children With ASD Using VRRS

Istituto per la Ricerca e l'In...

Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement

Emory University

NCT05501678 Phase 2

Trial of Diphenhydramine for Sleep in Children With Autism

Stanford University

Regulating Together for Intellectual Disability and Autism: A Group Behavioral Therapy for for Emotion Dysregulation

Children's Mercy Hospital Kans...

NCT05664841 Phase 2

The Impact of a Virtual Magic Trick Training Program

University of Alabama at Birmi...

Behavioral Activation for Treatment of Depression in Autistic Adolescents With Below Average Intelligence

Stony Brook University

Using Virtual Reality to Improve Emotion Understanding in Children With Autism

Istituto per la Ricerca e l'In...

Sensory Phenotypes of Autism Spectrum Disorder

National Taiwan University Hos...

Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth

Stanford University

Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

Stanford University

NCT06853665 Phase 4

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

Improving Academic and Social Functioning in Middle-Schoolers With Autism

Children's Hospital Medical Ce...

Promoting Emotional and Autonomic Control Through Guided Breathing Exercises for Emerging Adults With Autism

Universitaire Ziekenhuizen KU ...

Sleep Restriction Therapy (SRT) for Sleep Problems in Children With Autism

Stanford University

Related Conditions

autism spectrum disorder (10) autism spectrum disorder asd (3) asd (2) autistic spectrum disorder asd (1) epilepsy (1) intracranial tumors (1) cerebrovascular disease (1) adhd attention deficit disorder with hyperactivity (1) neuropsychiatric disorders (1) tic disorder childhood (1) mental retardation (1) developmental disabilities (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology