NCT07105358 Visual Plasticity Following Brain Lesions
| NCT ID | NCT07105358 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Georgetown University |
| Condition | Visual Field Defect |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-07-17 |
| Primary Completion | 2028-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-07-17 with a primary completion date of 2028-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.
Eligibility Criteria
A. Stroke, brain tumor, or traumatic brain injury patients Inclusion Criteria: 1. At least 18 years of age. 2. Capable of providing informed consent and complying with study procedures. 3. Unilateral or bilateral focal brain damage causing loss of vision. 4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year. Exclusion Criteria: 1. Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results. 2. Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5. 3. Vision loss resulting from ocular disease or disorder. B. Healthy volunteers (age-matched controls): Inclusion Criteria: 1. At least 18 years of age. 2. Capable of providing informed consent and complying with study procedures. Exclusion Criteria: 1. Any CNS diseases or psychiatric disorders (e.g., epilepsy, schizophrenia) that would interfere with study results. 2. Previous head injury. 3. Present or past (within past 6 months) drug or alcohol abuse or addiction based on DSM-5.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07105358 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Visual Field Defect. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07105358 currently recruiting?
Yes, NCT07105358 is actively recruiting participants. Contact the research team at tina.liu@georgetown.edu for enrollment information.
Where is the NCT07105358 trial being conducted?
This trial is being conducted at Washington D.C., United States.
Who is sponsoring the NCT07105358 clinical trial?
NCT07105358 is sponsored by Georgetown University. The trial plans to enroll 30 participants.