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Recruiting Phase 2, Phase 3 NCT07229664

NCT07229664 Vinpocetine in Patients With Parkinsonian Disease

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Clinical Trial Summary
NCT ID NCT07229664
Status Recruiting
Phase Phase 2, Phase 3
Sponsor Tanta University
Condition Parkinson Disease
Study Type INTERVENTIONAL
Enrollment 60 participants
Start Date 2025-11-10
Primary Completion 2026-11-20

Eligibility & Interventions

Sex All sexes
Min Age 50 Years
Max Age 70 Years
Study Type INTERVENTIONAL
Interventions
Levodopa CarbidopaVinpocetine

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 60 participants in total. It began in 2025-11-10 with a primary completion date of 2026-11-20.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The clinical manifestations of Parkinson's disease (PD), a chronic neurodegenerative condition, include resting tremor, hypokinesia, bradykinesia, stiffness and postural instability. These motor symptoms are caused by a selective loss and degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) region, which leads to a dopamine (DA) insufficiency in the striatum

Eligibility Criteria

Inclusion Criteria: Age ≥ 50 years Both male and female will be included Negative pregnancy test and effective contraception. Diagnosed Parkinson's disease patient taking Levodopa Exclusion Criteria: Secondary causes of parkinsonism Patients taking anti-inflammatory drugs Atypical parkinsonian syndromes Prior stereotaxic surgery for Parkinson's disease Pregnancy and lactation Cardiovascular disease patients Patients with coagulation disorders Suffering from active malignancy Addiction to alcohol and / or drugs Known allergy to the studied medications

Frequently Asked Questions

Who can join the NCT07229664 clinical trial?

This trial is open to participants of all sexes, aged 50 Years or older, up to 70 Years, studying Parkinson Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT07229664 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT07229664 currently recruiting?

Yes, NCT07229664 is actively recruiting participants. Visit ClinicalTrials.gov or contact Tanta University to inquire about joining.

Where is the NCT07229664 trial being conducted?

This trial is being conducted at Tanta, Egypt.

Who is sponsoring the NCT07229664 clinical trial?

NCT07229664 is sponsored by Tanta University. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology