NCT06192342 Ventilatory Parameters in Acute Neurological Injury
| NCT ID | NCT06192342 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ramos Mejía Hospital |
| Condition | Neurologic Decompensation, Acute |
| Study Type | OBSERVATIONAL |
| Enrollment | 19 participants |
| Start Date | 2024-05-01 |
| Primary Completion | 2026-05-30 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 19 participants in total. It began in 2024-05-01 with a primary completion date of 2026-05-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to test the association between baseline ventilatory parameters (in particular mechanical power (MP), mechanical power normalized to predicted body weight (MP/PBW) and driving pressure (DP) with the baseline neurological status (assessed through the Glasgow coma score) in adults patients under mechanical ventilation with acute neurological injury secondary to stroke, brain trauma or subarachnoid hemorrhage. The main question\[s\]it aims to answer are: 1. In patients with acute neurological injury under mechanical ventilation, is there a correlation between the acute neurological injury, assessed using the Glasgow scale on admission, and baseline ventilatory parameters? 2. In patients with acute neurological injury under mechanical ventilation, are the baseline ventilatory parameters altered at baseline?
Eligibility Criteria
Inclusion Criteria: Acute neurological injury in patients ≥ 16 years of age with requiring mechanical ventilation for neurological causes and without baseline lung injury, defined as: normal chest x-ray and adequate oxygenation; PaO2/FiO2 ≥ 300.Neumovent TS and Neumovent Advance respirators will be used. \- Exclusion Criteria: Pneumothorax, or a pleural drainage tube. Hemodynamic instability (mean blood pressure ≤ 65 mmHg) or high doses of inotropes (Norepinephrine \> 0.5 gammas/kilo/minute or equivalent). PaO2/FiO2 \< 80 mmHg. Chronic obstructive pulmonary disease (COPD). Pregnant
Contact & Investigator
Roberto Santa Cruz
PRINCIPAL INVESTIGATOR
Hospital General Ramos Mejia
Frequently Asked Questions
Who can join the NCT06192342 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, studying Neurologic Decompensation, Acute. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06192342 currently recruiting?
Yes, NCT06192342 is actively recruiting participants. Contact the research team at resc.hrrg@gmail.com for enrollment information.
Where is the NCT06192342 trial being conducted?
This trial is being conducted at Ciudad Autonoma de Buenos Aires, Argentina.
Who is sponsoring the NCT06192342 clinical trial?
NCT06192342 is sponsored by Ramos Mejía Hospital. The principal investigator is Roberto Santa Cruz at Hospital General Ramos Mejia. The trial plans to enroll 19 participants.