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Recruiting NCT03995121

NCT03995121 SV2 PET Imaging With [11C]APP311

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Clinical Trial Summary
NCT ID NCT03995121
Status Recruiting
Phase
Sponsor Yale University
Condition Schizophrenia and Other Psychotic Disorders
Study Type OBSERVATIONAL
Enrollment 250 participants
Start Date 2017-12-01
Primary Completion 2026-12

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 85 Years
Study Type OBSERVATIONAL
Interventions
[11C]APP311

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 250 participants in total. It began in 2017-12-01 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The aim of this study is to evaluate a new SV2A tracer, \[11C\]APP311, in healthy aging and neuropsychiatric disorders including psychotic disorders and cannabis use disorders.

Eligibility Criteria

Inclusion Criteria: * Willing and able to give voluntary written informed consent * Male and Female subjects, age 18 to 65 years, inclusive Exclusion Criteria: * MRI metal exclusions and claustrophobia. * Education completed is less than 12 years

Contact & Investigator

Central Contact

Angerlyk Frytz, MD

✉ angerlyk.frytz@yale.edu

📞 203-974-7822

Frequently Asked Questions

Who can join the NCT03995121 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Schizophrenia and Other Psychotic Disorders. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03995121 currently recruiting?

Yes, NCT03995121 is actively recruiting participants. Contact the research team at angerlyk.frytz@yale.edu for enrollment information.

Where is the NCT03995121 trial being conducted?

This trial is being conducted at New Haven, United States.

Who is sponsoring the NCT03995121 clinical trial?

NCT03995121 is sponsored by Yale University. The trial plans to enroll 250 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology