NCT07406100 Piloting the Competence in Romance and Understanding Sexual Health Curriculum
| NCT ID | NCT07406100 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Boston Children's Hospital |
| Condition | Autism |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2026-04-01 |
| Primary Completion | 2027-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2026-04-01 with a primary completion date of 2027-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn whether the CRUSH curriculum is possible (feasible), whether it fits the needs of the adults it is designed for (acceptable), and shows initial signs of being helpful (efficacious). CRUSH is a group-based behavioral intervention plus 1-1 coaching designed to provide sexual education and improve the skills of autistic adults for intimate relationships. The main goals of the project are to: * Evaluate the feasibility and acceptability of the CRUSH curriculum in the context of a clinical trial with a waitlist control condition. * Initial exploration of how the CRUSH curriculum works and whether it is helpful. Participants will complete: * A screening call. * Confirmation of clinical characteristics (autism features, language ability, cognitive ability). * 3 visits to assess knowledge and behaviors related to dating and sexual health at each point throughout the training curriculum (before beginning, midway, and after finishing). * 20 sessions of the CRUSH curriculum plus 1-1 coaching sessions. After each session, provide feedback about the session.
Eligibility Criteria
Inclusion Criteria: * 18;0 to 30;11 years old; * Either documentation of a prior diagnosis of autism spectrum disorder or receipt of services based on an autism spectrum diagnosis OR self identification as being autistic / on the autism spectrum and meeting the clinical cut-off on either the Autism Diagnostic Observation Schedule or the Autism Spectrum Quotient; * Ability to provide consent for the protocol and understand task demands. The Wechsler Abbreviated Scale of Intelligence, Second Edition (WASI-2) may be used to confirm cognitive level. In prior work, adults with full scale IQ of 70 or above on the WASI-2 typically meet this criterion, but a licensed clinician will review individuals who fall below an IQ of 70 on an individual basis to determine eligibility; * Fluent in English. Exclusion Criteria: * Non-English-speaking participants (less than 50% of speech in English); * Known genetic etiology of ASD (e.g., Fragile X); * Major mental illness (e.g., bipolar disorder, schizophrenia, or psychosis); * Medical conditions that impact sexual function (e.g., pituitary tumor); * Significant sensory, motor, or physical conditions that would prevent valid participation in assessments or intervention; * Live more than 50 miles from the site in Brookline, MA where intervention and assessment sessions will be offered. * Receipt of other sexual health/dating curricula as an adult.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07406100 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 30 Years, studying Autism. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07406100 currently recruiting?
Yes, NCT07406100 is actively recruiting participants. Contact the research team at ProjectCRUSH@childrens.harvard.edu for enrollment information.
Where is the NCT07406100 trial being conducted?
This trial is being conducted at Brookline, United States.
Who is sponsoring the NCT07406100 clinical trial?
NCT07406100 is sponsored by Boston Children's Hospital. The trial plans to enroll 40 participants.