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Recruiting NCT05846841

NCT05846841 Personalized Tobacco Treatment in Primary Care (MOTIVATE)

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Clinical Trial Summary
NCT ID NCT05846841
Status Recruiting
Phase
Sponsor Washington University School of Medicine
Condition Physician's Role
Study Type INTERVENTIONAL
Enrollment 850 participants
Start Date 2023-09-29
Primary Completion 2028-03-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Precision TreatmentUsual Care

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 850 participants in total. It began in 2023-09-29 with a primary completion date of 2028-03-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study examines the application of precision treatment intervention for smoking cessation from both the clinician perspective and patient perspective, and compares it to usual care on tobacco treatment in the primary care setting. The precision treatment intervention includes personalized tobacco treatment recommendations using the patient's clinical, genetic, and biomarker information. This approach may increase effectiveness and adherence for the patient, and increase the clinician's likelihood of prescribing.

Eligibility Criteria

Eligibility Criteria for Primary and Specialty Care Clinicians * Clinician from participating clinic * At least 18 years of age * Can speak and understand English Eligibility Criteria for Primary Care and Specialty Patients Inclusion: * Patient at participating clinic * Age 18 years or older, inclusive * Current smoking (cigarettes per day \>=5) * Can speak and understand English * Willing to consider medication to help reduce craving or smoking such as nicotine patch, lozenge, or varenicline Exclusion: * Active use of smoking cessation medication (within the past 30 days) * Receipt of smoking cessation medication or prescription for smoking cessation medication (within the past 30 days) * Having a contraindication for cNRT or varenicline (allergic reactions, current cardiac problems, pregnancy)

Contact & Investigator

Central Contact

Li-Shiun Chen, ScD, MD, MPH

✉ li-shiun@wustl.edu

📞 314-362-3932

Principal Investigator

Li-Shiun Chen, ScD, MD, MPH

PRINCIPAL INVESTIGATOR

Washington University School of Medicine

Frequently Asked Questions

Who can join the NCT05846841 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Physician's Role. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05846841 currently recruiting?

Yes, NCT05846841 is actively recruiting participants. Contact the research team at li-shiun@wustl.edu for enrollment information.

Where is the NCT05846841 trial being conducted?

This trial is being conducted at St Louis, United States.

Who is sponsoring the NCT05846841 clinical trial?

NCT05846841 is sponsored by Washington University School of Medicine. The principal investigator is Li-Shiun Chen, ScD, MD, MPH at Washington University School of Medicine. The trial plans to enroll 850 participants.

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