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Recruiting NCT02383342

Pain Predict Genetics

Trial Parameters

Condition Chronic Pain
Sponsor Radboud University Medical Center
Study Type OBSERVATIONAL
Phase N/A
Enrollment 10,000
Sex ALL
Min Age 18 Years
Max Age 80 Years
Start Date 2015-05-12
Completion 2027-03

Brief Summary

Pain is the most frequent cause of suffering and disability in society. Despite considerable involvement of genetic factors in pain sensation and sensitivity, the individual genes involved remain largely unidentified. In this project the investigators will follow patients undergoing elective major surgery for the development of acute and chronic pain. The investigators will search for clinical as well as genetic factors that can predict the development of pain. These can serve as biomarkers to predict acute and chronic pain development and progression in individual patients and help early individual treatment adaptation.

Eligibility Criteria

Inclusion Criteria: Patients: * Ages 18 - 80 years, consenting, planned surgery, able to understand and answer questionnaires. Exclusion Criteria: * Non-consent, inability to give consent, unplanned and emergency surgery.

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