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Medical Condition
acute pain
Total Trials
8
Recruiting Now
8
Trial Phases
Various
Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.
Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.
Frequently Asked Questions — acute pain Clinical Trials
How many clinical trials are currently recruiting for acute pain?
ClinicalMetric currently tracks 8 actively recruiting clinical trials for acute pain, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for acute pain?
acute pain research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a acute pain clinical trial?
Eligibility criteria for acute pain trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT06184126
Recruiting
Enrollment
30 pts
Location
United States
Sponsor
University of Maryland, Baltim...
NCT05750992
Recruiting
Enrollment
50 pts
Location
Egypt
Sponsor
Al-Azhar University
NCT07336264
Recruiting
Enrollment
100 pts
Location
United States
Sponsor
Children's National Research I...
NCT03725527
Recruiting
Enrollment
60 pts
Location
Egypt
Sponsor
Assiut University
NCT07291388
Recruiting
Enrollment
44 pts
Location
Chile
Sponsor
Pontificia Universidad Catolic...
NCT06164028
Recruiting
Enrollment
60 pts
Location
United States
Sponsor
Duke University
NCT07698665
Recruiting
Enrollment
90 pts
Location
Egypt
Sponsor
Cairo University
NCT07739277
Recruiting
Enrollment
70 pts
Location
Turkey (Türkiye)
Sponsor
Ankara Etlik City Hospital
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology