NCT07344467 Oral Melatonin Versus Oral Pregabalin on Postoperative Pain and Anxiety Following Spine Surgery
| NCT ID | NCT07344467 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Tanta University |
| Condition | Oral |
| Study Type | INTERVENTIONAL |
| Enrollment | 105 participants |
| Start Date | 2026-01-17 |
| Primary Completion | 2027-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 105 participants in total. It began in 2026-01-17 with a primary completion date of 2027-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to compare the efficacy of using Melatonin versus Pregabalin on postoperative pain and anxiety after spine surgeries.
Eligibility Criteria
Inclusion Criteria: * Patients aged 21-60 years old. * Both sexes. * Patients of American Society of Anesthesiologists (ASA) physical status I \& II. * Undergoing elective spine surgery. Exclusion Criteria: * Patient refusal. * History of allergic reactions to melatonin or pregabalin. * Patients with cardiovascular disease (ischemic heart disease, Heart Failure, Arrythmia, Heart Block). * Patients with kidney disease with (plasma creatinine level \> 1.5mg/dl). * Patients with liver disease with (aspartate transaminase, alanine transaminase, and bilirubin levels more than twice the upper limit of normal). * Psychological and cognitive disorders; dementia; major depression. * Circadian rhythm disorders such as chronic fatigue syndrome and drowsiness.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07344467 clinical trial?
This trial is open to participants of all sexes, aged 21 Years or older, up to 60 Years, studying Oral. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07344467 currently recruiting?
Yes, NCT07344467 is actively recruiting participants. Contact the research team at Ahmed.hamdy@med.tanta.edu.eg for enrollment information.
Where is the NCT07344467 trial being conducted?
This trial is being conducted at Tanta, Egypt.
Who is sponsoring the NCT07344467 clinical trial?
NCT07344467 is sponsored by Tanta University. The trial plans to enroll 105 participants.