NCT02132741 Optical Coherence Tomography And NEphropathy: The OCTANE Study
| NCT ID | NCT02132741 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Edinburgh |
| Condition | Health |
| Study Type | OBSERVATIONAL |
| Enrollment | 150 participants |
| Start Date | 2014-05-16 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 150 participants in total. It began in 2014-05-16 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients with high blood pressure (hypertension) and chronic kidney disease are at an increased risk of developing heart disease and strokes. Part of this risk is due to changes in the structure and function of the blood vessels throughout the body. It is thought that reducing high blood pressure and treating chronic kidney disease improves the structure and function of blood vessels but information on this is limited. Optical coherence tomography (OCT) is a method of looking at the blood vessels at the back of the eye. It is a simple, quick and non-invasive test that you may have previously had during a visit to the optician. The purpose of the study is to ascertain whether OCT is able to detect changes in the eye's blood vessels in patients with hypertension and chronic kidney disease compared to healthy individuals and also to see if any differences seen improve with treatment.
Eligibility Criteria
Inclusion Criteria: * Male or female * Age 18-80 * Body mass index ≤35 * For those with hypertension: BP ≥140/90 or on treatment for hypertension * For those with CKD: CKD as defined by the Kidney Diseases Quality Initiative guidelines Exclusion Criteria: * Subject is below the age of legal consent, or is mentally or legally incapacitated * The subject has donated blood (450 ml) within the last 4 weeks * Past or present drug or alcohol abuse including intravenous drug abuse at any time * Participation in another clinical trial within 1 month * Considered to be at high risk of HIV or hepatitis B * Patients with known eye disease, or previous eye surgery, or refractive error greater than +/- 6 dioptres.
Contact & Investigator
Neeraj Dhaun, MD PhD
PRINCIPAL INVESTIGATOR
University of Edinburgh
Frequently Asked Questions
Who can join the NCT02132741 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Health. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT02132741 currently recruiting?
Yes, NCT02132741 is actively recruiting participants. Contact the research team at bean.dhaun@ed.ac.uk for enrollment information.
Where is the NCT02132741 trial being conducted?
This trial is being conducted at Edinburgh, United Kingdom.
Who is sponsoring the NCT02132741 clinical trial?
NCT02132741 is sponsored by University of Edinburgh. The principal investigator is Neeraj Dhaun, MD PhD at University of Edinburgh. The trial plans to enroll 150 participants.