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Recruiting NCT04986332

Multidimensional Approach for COPD and High Complexity

Trial Parameters

Condition Chronic Obstructive Pulmonary Disease
Sponsor Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Study Type INTERVENTIONAL
Phase N/A
Enrollment 300
Sex ALL
Min Age 45 Years
Max Age 75 Years
Start Date 2021-09-01
Completion 2023-09-01
Interventions
Physical activity programGlobal therapeutic remodeling

Brief Summary

The MACH Study trial will examine the impact on high complexity COPD patients of a multidimensional approach (moderate-intensity physical activity program and clinic-therapeutic re-evaluation of the participants)

Eligibility Criteria

Inclusion Criteria: * Provide signed and dated informed consent form; * Willing to comply with all study procedures and be available for the duration of the study; * COPD diagnosis (according to "Global Initiative for Chronic Obstructive Lung Disease" (GOLD) 2020 Guidelines) or HF diagnosis (according to European Society of Cardiology (ESC) 2016 Guidelines for the diagnosis and treatment of acute and chronic heart failure); * Diagnosis at least two other chronic diseases, in addition to COPD (Group A) or HF (Group B). If COPD and HF diagnoses are both present in the same subject, COPD or HF will be considered as the index pathology in view of the clinical relevance and ergo, the participant will be included in the group A or in the group B; * Healthy subjects exclusively for Group C; Chronic diseases are considered the following: * Type 1 or Type 2 Diabetes mellitus * Essential hypertension * Chronic Kidney Disease Stage 3b or worst (Glomerular Filtration Rate \< 44 mL/min/1.73 m\^2 es

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