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Recruiting NCT07371390

NCT07371390 Minimal Sedation During Knee Replacement Surgery

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Clinical Trial Summary
NCT ID NCT07371390
Status Recruiting
Phase
Sponsor Mayo Clinic
Condition Total Knee Arthroplasty
Study Type INTERVENTIONAL
Enrollment 200 participants
Start Date 2025-12-11
Primary Completion 2026-11-24

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Active Noise Cancelling Headset System

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 200 participants in total. It began in 2025-12-11 with a primary completion date of 2026-11-24.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study will test the use of active noise cancelling headphones with music or a movie during knee replacement surgery. Feedback from the surgical team and from patients regarding the headset system will be gathered to see if using it can reduce the amount of sedation needed during knee replacement procedures that use localized anesthesia.

Eligibility Criteria

Inclusion Criteria: * Primary Total Knee Arthroplasty * Indicated for Spinal Anesthesia * 18+ years old * Participant can independently provide informed consent Exclusion Criteria: * Unicompartmental Knee Arthroplasty * Revision Knee Arthroplasty

Contact & Investigator

Central Contact

Gabriel D Schouten

✉ schouten.gabriel@mayo.edu

📞 507-266-5895

Principal Investigator

Matthew P Abdel, MD

PRINCIPAL INVESTIGATOR

Mayo Clinic

Frequently Asked Questions

Who can join the NCT07371390 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Total Knee Arthroplasty. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07371390 currently recruiting?

Yes, NCT07371390 is actively recruiting participants. Contact the research team at schouten.gabriel@mayo.edu for enrollment information.

Where is the NCT07371390 trial being conducted?

This trial is being conducted at Rochester, United States.

Who is sponsoring the NCT07371390 clinical trial?

NCT07371390 is sponsored by Mayo Clinic. The principal investigator is Matthew P Abdel, MD at Mayo Clinic. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology