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total knee arthroplasty
Total Trials
8
Recruiting Now
8
Trial Phases
Phase 2
ClinicalMetric tracks all active clinical trials for total knee arthroplasty sourced from ClinicalTrials.gov. Each listing includes the NCT identifier, current recruitment status, phase, primary endpoints, sponsor, estimated enrollment, and participating countries — updated daily as new studies open and status changes.
- Recruiting trials currently enrolling participants, with eligibility criteria and age requirements
- Phase 1–4 studies from early safety trials to post-marketing surveillance
- NIH, pharmaceutical sponsor, and academic medical center studies worldwide
- AI-powered plain-language summary available for every trial listing
Frequently Asked Questions — total knee arthroplasty Clinical Trials
How many clinical trials are currently recruiting for total knee arthroplasty?
ClinicalMetric currently tracks 8 actively recruiting clinical trials for total knee arthroplasty, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for total knee arthroplasty?
total knee arthroplasty research spans Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a total knee arthroplasty clinical trial?
Eligibility criteria for total knee arthroplasty trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2 1
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT05288803
Recruiting
Improving Rehabilitation for Veterans After Total Knee Arthroplasty Using Individualized Recovery Trajectories
Enrollment
200 pts
Location
United States
Sponsor
VA Office of Research and Deve...
NCT05391828
Recruiting
Persona MC vs PS RCT With ROSA
Enrollment
200 pts
Location
United States
Sponsor
NYU Langone Health
NCT07124494
Recruiting
Regional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction
Enrollment
30 pts
Location
Turkey (Türkiye)
Sponsor
Konya City Hospital
NCT07367789
Recruiting
Prediction of Postoperative Outcomes After TKA Using Instrumented Insoles and DNN
Enrollment
200 pts
Location
South Korea
Sponsor
Yonsei University
NCT07020312 Phase 2
Recruiting
Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery
Enrollment
240 pts
Location
United States
Sponsor
Rush University Medical Center
NCT07437469
Recruiting
Binaural Beats for Postoperative Pain and Anxiety Reduction
Enrollment
50 pts
Location
United States
Sponsor
University of Miami
NCT07021287
Recruiting
Effect of Different Cold Therapy Programs in Patients Received Total Knee Arthroplasty Operation
Enrollment
260 pts
Location
China
Sponsor
The Fourth Affiliated Hospital...
NCT04801654
Recruiting
GMK Sphere TiNb Total Knee Arthroplasty PMS Study
Enrollment
155 pts
Location
Italy
Sponsor
Medacta International SA
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: April 2026 · Data Methodology