NCT07692269 Mindfulness Intervention for Emotional Distress: An EEG Study
| NCT ID | NCT07692269 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Peking University |
| Condition | Emotional Distress |
| Study Type | INTERVENTIONAL |
| Enrollment | 160 participants |
| Start Date | 2026-07-04 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 160 participants in total. It began in 2026-07-04 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a randomized controlled trial examining the efficacy and neural mechanisms of a standardized Mindfulness Intervention for Emotional Distress (MIED) in adults with subclinical emotional distress. One hundred and sixty participants will be randomly assigned to either an 8-week MIED program or an 8-week Progressive Muscle Relaxation (PMR) active control. The primary aim is to evaluate whether MIED reduces anxiety symptoms and reshapes multilevel emotional processing as measured by multimodal EEG (resting-state FAA/theta, Fast Periodic Visual Stimulation, and event-related potentials). Assessments occur at baseline (T1), post-intervention (T2), and 1-month follow-up.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18-50 years Kessler Psychological Distress Scale (K10) score \> 21 No systematic mindfulness or progressive muscle relaxation practice in the past 6 months (frequency \< 1 time per week) Normal or corrected-to-normal vision Voluntary participation with signed informed consent Exclusion Criteria: * Prior diagnosis of schizophrenia, bipolar disorder, or other severe mental disorders by a psychiatrist Suicidal plan, self-injury, or need for emergency psychological crisis intervention in the past month Currently receiving systematic psychotherapy or participating in other psychological intervention programs Started psychiatric medication within the past 3 months or on an unstable medication dosage History of epilepsy, severe brain injury, or other neurological disorders that may affect EEG measurement Severe vision or hearing impairment or other conditions preventing completion of study procedures
Contact & Investigator
Xinghua Liu, Dr.
PRINCIPAL INVESTIGATOR
School of Psychological and Cognitive Science,Peking University
Frequently Asked Questions
Who can join the NCT07692269 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 50 Years, studying Emotional Distress. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07692269 currently recruiting?
Yes, NCT07692269 is actively recruiting participants. Contact the research team at qszheng25@stu.pku.edu.cn for enrollment information.
Where is the NCT07692269 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT07692269 clinical trial?
NCT07692269 is sponsored by Peking University. The principal investigator is Xinghua Liu, Dr. at School of Psychological and Cognitive Science,Peking University. The trial plans to enroll 160 participants.