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RecruitingPhase 3NCT05058287

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

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Plain-language summary for patients

Trial Parameters

ConditionOpioid Use
SponsorHospital for Special Surgery, New York
Study TypeINTERVENTIONAL
PhasePhase 3
Enrollment150
SexALL
Min Age18 Years
Max Age85 Years
Start Date2021-11-05
Completion2026-12-31
Interventions
Depo-Medrol 40Mg/Ml Suspension for InjectionPlacebo

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Brief Summary

This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy. The study will examine post-operative opioid usage, length of stay, return to work, and patient reported outcomes following these procedures.

Eligibility Criteria

Inclusion Criteria: * Patients scheduled to undergo 1 to 2 level laminectomy * Between the ages of 18-85 Exclusion Criteria: * Minimally invasive surgery * Prior daily opioid usage within 6 months. * Use of concomitant procedures such as spinal fusion, revision procedure at the same level. * History of a chronic pain syndrome, uncontrolled diabetes defined as A1C \> 6.5, immunocompromised condition such as active cancer treatment, history of transplant, benign prostatic hyperplasia or history of urinary retention, and other conditions which require chronic steroid therapy or immunosuppressants. * Non-English speakers * Patients allergic to Depo-Medrol and/or glucocorticoids, or other steroids

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