NCT07177183 Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure
| NCT ID | NCT07177183 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University Hospital Ostrava |
| Condition | Prolonged Mechanical Ventilation |
| Study Type | INTERVENTIONAL |
| Enrollment | 492 participants |
| Start Date | 2026-02-02 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 492 participants in total. It began in 2026-02-02 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main objective of the study is to determine whether a subnormal serum creatinine value upon admission to the Post-ICU Care Unit predicts the need for prolonged ventilatory support. A parallel objective of the study is to determine whether exogenous in-take of the dietary supplement creatine in patients with subnormal serum creatinine value is associated with a shortened duration of ventilatory support and improved patients outcome.
Eligibility Criteria
Inclusion Criteria: * Patients \<18 years of age * Patients admitted to post-ICU care units at Chronicare Group a.s. in the Czech Republic within 12 months Exclusion Criteria: * Patients who are unlikely to be weaned from ventilatory support. * Patients in palliative care or with a survival probability of \<3 months * Patients with advanced malignancy * Patients with a history of chronic kidney disease * Patients with a history of chronic liver disease * Patients with supranormal serum creatinine on admission to the post-ICU care unit * Patients who refused to sign the Informed Consent with participation in the study.
Contact & Investigator
Roman Kula, MD, CSc
STUDY CHAIR
University Hospital Ostrava
Frequently Asked Questions
Who can join the NCT07177183 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Prolonged Mechanical Ventilation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07177183 currently recruiting?
Yes, NCT07177183 is actively recruiting participants. Contact the research team at jiri.hyncica@fno.cz for enrollment information.
Where is the NCT07177183 trial being conducted?
This trial is being conducted at Brno, Czechia, Milovice, Czechia.
Who is sponsoring the NCT07177183 clinical trial?
NCT07177183 is sponsored by University Hospital Ostrava. The principal investigator is Roman Kula, MD, CSc at University Hospital Ostrava. The trial plans to enroll 492 participants.