Medical Condition

critical illness

Total Trials

30

Recruiting Now

30

Trial Phases

Phase 4, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for critical illness sourced from ClinicalTrials.gov. Each listing includes the NCT identifier, current recruitment status, phase, primary endpoints, sponsor, estimated enrollment, and participating countries — updated daily as new studies open and status changes.

Recruiting trials currently enrolling participants, with eligibility criteria and age requirements
Phase 1–4 studies from early safety trials to post-marketing surveillance
NIH, pharmaceutical sponsor, and academic medical center studies worldwide
AI-powered plain-language summary available for every trial listing

Frequently Asked Questions — critical illness Clinical Trials

How many clinical trials are currently recruiting for critical illness?

ClinicalMetric currently tracks 30 actively recruiting clinical trials for critical illness, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 30. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for critical illness?

critical illness research spans Phase 1 (1 trial), Phase 2 (2 trials), Phase 3 (2 trials), Phase 4 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a critical illness clinical trial?

Eligibility criteria for critical illness trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 1

Phase 2

Phase 3

Phase 4

Top Sponsors

Mayo Clinic 1 trial

Universität Münster 1 trial

Dr. Stephanie Sibley 1 trial

Romanian Society for Enteral and Parenteral Nutrition 1 trial

Hospital Moinhos de Vento 1 trial

critical illness

Frequently Asked Questions — critical illness Clinical Trials

Recruiting Clinical Trials

A Study of Healthy Microbiome, Healthy Mind

Standard Dose Continuous Renal Replacement Therapy (CRRT) Versus Low-Dose CRRT ( KETZEREI )

Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients

Achieving nuTritional Target in criticAlly Ill patieNts With iMpairEd gastroiNtesTinal Dysfunction

Neuromuscular Electrical Stimulation in a Patient on Invasive Mechanical Ventilation (MOVCARE)

Neurocognitive Outcomes for ICU Patients With Acute Kidney Injury

The Effect of the Timing of Supplemental Parenteral Nutrition on the Prognosis of Critically Ill Patients (T-SPN)

Embedded Palliative Care in the MICU

Effect of Dynamic Arterial Elastance and Assisted Fluid Management Software Guided Resuscitation in Septic Shock: Pilot Study

Use of Vasopressin in Patients at High Risk of Acute Kidney Injury Admitted to the ICU

Episodes of (Dis)Connected Consciousness in ICU Survivors

Intra-Hospital Transport of Critically Ill Patients in Intensive Care Unit

IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients

Evaluating the Unmet Needs of Older Adults to Promote Functional Recovery After a Critical Illness

Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation

Developing Strategies to Facilitate Consent of Legally Authorized Representatives to Clinical Trials

iNO300 Therapy in Critically Ill Patients With Pneumonia

Goal-Directed Sedation in Mechanically Ventilated Infants and Children

COPM-Based Goal Setting Strategies in the PICU

Incidence and Determinants of Joint Contractures in Mechanically Ventilated ICU Patients

Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients

Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults

Relationship Between Pulse Pressure and Stroke Volume in the Critically Ill Patients: The ANDROMEDA-PEGASUS Study

Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.

Enhanced Protein Intake to Support Muscle Protein Synthesis in ICU

Low Serum Creatinine as a Predictor of Prolonged Mechanical Ventilation and Weaning Failure

NIBP Validation Study

The Intensive Care Platform Trial

Muscle and Subcutaneous Tissue Variation by Ultrasound and Impedance Linked to Fluid Balance in ICU Patients

Optimised Nutritional Therapy and Early Physiotherapy in Long Term ICU Patients (NutriPhyT Trial)