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Recruiting NCT06978166

NCT06978166 Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain

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Clinical Trial Summary
NCT ID NCT06978166
Status Recruiting
Phase
Sponsor Washington University School of Medicine
Condition Chronic Pain
Study Type INTERVENTIONAL
Enrollment 1,000 participants
Start Date 2025-06-02
Primary Completion 2026-12

Eligibility & Interventions

Sex All sexes
Min Age 45 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Just-In-Time Adaptive Interventions (JITAIs)Wysa for Chronic Pain

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 1,000 participants in total. It began in 2025-06-02 with a primary completion date of 2026-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The purpose of this research study is to refine customized in-app notifications in order to optimize users' experience with a mobile app called Wysa for Chronic Pain. This app is designed to support people who have chronic pain and who also experience symptoms of depression and/or anxiety. This version of the app is not currently available to the public. Eligible participants will be asked to download and use the Wysa for Chronic Pain study app for several weeks, and to use it as they normally would if they were not part of a research study. At the beginning and end of the study period, participants will be asked to complete brief surveys about their mood, pain, physical function, and sleep. Additionally, a few participants will be asked to share their experience with the study app at the end of the research study in a casual interview using a secure audio/video recorded call. Participating in the interview portion is optional.

Eligibility Criteria

Inclusion Criteria: * 45 years or older * At least moderately severe depression and/or anxiety symptoms (Patient Health Questionnaire-9 (PHQ-9) and/or Generalized Anxiety Disorder-7 (GAD-7) score ≥ 10) * Chronic pain (i.e., pain on most days or every day in the past three months) Exclusion Criteria: * Frequent active suicidal ideation * No access to a mobile device * Not living in the United States

Contact & Investigator

Central Contact

Adriana Martin

✉ azmartin@wustl.edu

📞 314-530-9023

Principal Investigator

Abby L. Cheng, MD, MPHS

PRINCIPAL INVESTIGATOR

Washington University School of Medicine

Frequently Asked Questions

Who can join the NCT06978166 clinical trial?

This trial is open to participants of all sexes, aged 45 Years or older, studying Chronic Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06978166 currently recruiting?

Yes, NCT06978166 is actively recruiting participants. Contact the research team at azmartin@wustl.edu for enrollment information.

Where is the NCT06978166 trial being conducted?

This trial is being conducted at St Louis, United States.

Who is sponsoring the NCT06978166 clinical trial?

NCT06978166 is sponsored by Washington University School of Medicine. The principal investigator is Abby L. Cheng, MD, MPHS at Washington University School of Medicine. The trial plans to enroll 1,000 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology