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Recruiting NCT03384108

NCT03384108 In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells

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Clinical Trial Summary
NCT ID NCT03384108
Status Recruiting
Phase
Sponsor Mayo Clinic
Condition Healthy
Study Type INTERVENTIONAL
Enrollment 20 participants
Start Date 2017-09-01
Primary Completion 2028-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 60 Years
Study Type INTERVENTIONAL
Interventions
5-13C-GlutamineBone marrow aspiration

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 20 participants in total. It began in 2017-09-01 with a primary completion date of 2028-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach

Eligibility Criteria

Inclusion Criteria: * Ages 18-60 * Able to provide written consent Exclusion Criteria: * Renal Failure * Pregnancy * Active steroid use * Active liver Disease * Anemia (Hemoglobin \< 12.5 g/dL in men and \< 11.5 g/dL in women) * H/O alcohol use (average \> 2 drinks per day) * BMI \> 30

Contact & Investigator

Central Contact

Wilson Gonsalves

✉ gonsalves.wilson@mayo.edu

📞 5072842511

Principal Investigator

Wilson Gonsalves, MD

PRINCIPAL INVESTIGATOR

Mayo Clinic

Frequently Asked Questions

Who can join the NCT03384108 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Healthy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03384108 currently recruiting?

Yes, NCT03384108 is actively recruiting participants. Contact the research team at gonsalves.wilson@mayo.edu for enrollment information.

Where is the NCT03384108 trial being conducted?

This trial is being conducted at Rochester, United States.

Who is sponsoring the NCT03384108 clinical trial?

NCT03384108 is sponsored by Mayo Clinic. The principal investigator is Wilson Gonsalves, MD at Mayo Clinic. The trial plans to enroll 20 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology