NCT05703386 Imaging the Pathogenesis of Cerebral Small Vessel Disease
| NCT ID | NCT05703386 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Johns Hopkins University |
| Condition | Ischemic Stroke |
| Study Type | OBSERVATIONAL |
| Enrollment | 50 participants |
| Start Date | 2022-11-08 |
| Primary Completion | 2027-03-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 50 participants in total. It began in 2022-11-08 with a primary completion date of 2027-03-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Cerebral small vessel disease (CSVD) can lead to vascular cognitive impairment and dementia (VCID). The hallmark of CSVD is the appearance and progression of white matter hyperintensities (WMH) on MRI. The goal of this study it to recruit and follow individuals at risk for WMH progression and use serial MRI scanning to gain insights into the pathogenesis of CSVD.
Eligibility Criteria
Inclusion Criteria: * Clinical or radiographic evidence of ischemic stroke * One vascular risk factor (hypertension, hyperlipidemia, or diabetes) * Evidence of cerebral small vessel disease on MRI Exclusion Criteria: * Inability to complete 3 research MRI scans over 1.25 years
Contact & Investigator
Richard Leigh, MD
PRINCIPAL INVESTIGATOR
Johns Hopkins University
Frequently Asked Questions
Who can join the NCT05703386 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Ischemic Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05703386 currently recruiting?
Yes, NCT05703386 is actively recruiting participants. Contact the research team at schase15@jh.edu for enrollment information.
Where is the NCT05703386 trial being conducted?
This trial is being conducted at Baltimore, United States.
Who is sponsoring the NCT05703386 clinical trial?
NCT05703386 is sponsored by Johns Hopkins University. The principal investigator is Richard Leigh, MD at Johns Hopkins University. The trial plans to enroll 50 participants.
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