NCT05113043 Correlation Between Intestinal Microecology Imbalance and Stroke in Young Adults
| NCT ID | NCT05113043 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shanghai 6th People's Hospital |
| Condition | Ischemic Stroke |
| Study Type | OBSERVATIONAL |
| Enrollment | 60 participants |
| Start Date | 2022-02-01 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 60 participants in total. It began in 2022-02-01 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The relationship between the intestinal microecology and stroke has become a research hotspot in neurology field today. Maintaining the balance of the intestinal microbiota are expected to bring new breakthroughs for prevention and treatment of stroke. In recent years, stroke in young adults has an increasing incidence and a considerable socioeconomic impact because of high disability rate and health-care costs. So there is an urgent need to explore the role and mechanism of intestinal microecology imbalance in stroke, especially in the development and prognosis of stroke in young people. This study aims to use multi-omics technologies, including microbial diversity, metagenomics and metabonomics, to reveal the characteristics of intestinal flora in young stroke patients, identify biomarkers for predicting outcome after stroke and early detection of young people at high risk of stroke, and to further explore the role of gut-brain axis in the pathogenesis of stroke.
Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of acute ischemic or hemorrhagic stroke * Admission within 12 hours * Aged 18-45 years Exclusion Criteria: * History of neurological diseases, myocardial infarction, renal and hepatic abnormalities and metabolic diseases * Combined with tumors, inflammatory bowel disease and other digestive system diseases * Combined with serious life-threatening diseases or condition * Any antibiotics, probiotics or prebiotic treatment within 3 months * Deteriorate and die before collecting faecal samples
Contact & Investigator
Lixia Xue, M.D., Ph.D.
STUDY DIRECTOR
Shanghai 6th People's Hospital
Frequently Asked Questions
Who can join the NCT05113043 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 45 Years, studying Ischemic Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05113043 currently recruiting?
Yes, NCT05113043 is actively recruiting participants. Contact the research team at chenhao_316@aliyun.com for enrollment information.
Where is the NCT05113043 trial being conducted?
This trial is being conducted at Shanghai, China, Shanghai, China.
Who is sponsoring the NCT05113043 clinical trial?
NCT05113043 is sponsored by Shanghai 6th People's Hospital. The principal investigator is Lixia Xue, M.D., Ph.D. at Shanghai 6th People's Hospital. The trial plans to enroll 60 participants.
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