NCT07363941 HEIGHT-BASED AND CONVENTIONAL SPINAL ANAESTHETIC DOSING IN GERIATRIC PATIENTS
| NCT ID | NCT07363941 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shaheed Mohtarma Benazir Bhutto Institue of Trauma |
| Condition | Geriatric Population |
| Study Type | INTERVENTIONAL |
| Enrollment | 104 participants |
| Start Date | 2026-01-03 |
| Primary Completion | 2026-05-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 104 participants in total. It began in 2026-01-03 with a primary completion date of 2026-05-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to find out whether height-based dosing of spinal anaesthesia provides better hemodynamic stability and anesthetic outcome than conventional fixed dosing in elderly patients undergoing lower limb orthopaedic surgery.The main questions this study aims to answer are: 1. Does height-based spinal anaesthetic dosing reduce the risk of hypotension and bradycardia during surgery as compared to conventional fixed dosing? 2. Does it improve anaesthetic outcomes, such as the onset and duration of sensory and motor block?
Eligibility Criteria
Inclusion Criteria: Individuals aged 60 to 80 years. Either gender (male or female). Patients who are ASA physical status I-III. Individuals scheduled to undergo elective lower limb orthopaedic surgeries (e.g., fracture fixation, total knee replacement, open reduction and internal fixation). Patients planned to receive spinal anaesthesia as the primary anaesthetic technique. Those who provide informed written consent for participation in the study. Exclusion Criteria: Individuals exhibiting a stature inferior to 150 cm. Patients receiving anti-hypertensive drugs or those on beta blockers or beta-agonists. Patients with a history of neurological disease like CVA or Parkinsonism. Patients presenting with sepsis (≥ 2 positive SIRS criteria with positive aseptically obtained blood or wound culture). Patients with a history of coagulation disorders like haemophilia or vWD or those with a history of anti-platelet drug intake in the last 2 weeks. Individuals possessing a documented history of hypersensitivity reactions to pharmacological agents utilized in the research. Patients who will be diagnosed with a skin infection at the spinal needle puncture site. Patients undergoing emergency orthopaedic procedures requiring immediate intervention
Frequently Asked Questions
Who can join the NCT07363941 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, up to 80 Years, studying Geriatric Population. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07363941 currently recruiting?
Yes, NCT07363941 is actively recruiting participants. Visit ClinicalTrials.gov or contact Shaheed Mohtarma Benazir Bhutto Institue of Trauma to inquire about joining.
Where is the NCT07363941 trial being conducted?
This trial is being conducted at Karachi, Pakistan.
Who is sponsoring the NCT07363941 clinical trial?
NCT07363941 is sponsored by Shaheed Mohtarma Benazir Bhutto Institue of Trauma. The trial plans to enroll 104 participants.