NCT06819436 Effect of Dexamethasone on Post-spinal Hypotension
| NCT ID | NCT06819436 |
| Status | Recruiting |
| Phase | Phase 4 |
| Sponsor | Shaheed Mohtarma Benazir Bhutto Institue of Trauma |
| Condition | Post Spinal Anaesthesia Hypotension |
| Study Type | INTERVENTIONAL |
| Enrollment | 170 participants |
| Start Date | 2025-02 |
| Primary Completion | 2025-04 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
Phase 4 studies follow an already-approved treatment in real-world conditions to monitor long-term safety and effectiveness.
This trial targets 170 participants in total. It began in 2025-02 with a primary completion date of 2025-04.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries. The main question aim to answer is: Does intravenous dexamethasone in participants undergoing orthopedic procedures of lower limb under spinal anesthesia prevents post spinal hypotension? Researchers are comparing two groups of participants * Participants in (Dexamethasone Group) Group D are receiving intravenous dexamethasone 8mg preoperatively * Participants in (Placebo Group) Group P are receiving placebo preoperatively.
Eligibility Criteria
Inclusion Criteria: Patient undergoing orthopedic surgery in spinal anesthesia. ASA ≤ 2. Exclusion Criteria: Patients with history of cardiac arrhythmias. Patients with history of acute coronary syndrome. Patient with history of polytrauma. Patients with contraindication to SA (e.g., coagulopathy, thrombocytopenia, allergy to local anesthetic agent) and those on steroids or serotonin related medications (e.g., selective serotonin reuptake inhibitor) will be excluded.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06819436 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, up to 85 Years, studying Post Spinal Anaesthesia Hypotension. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT06819436 trial and what does that mean for participants?
Phase 4 studies are conducted after a treatment has been approved. They monitor long-term safety and real-world effectiveness in a broader patient population.
Is NCT06819436 currently recruiting?
Yes, NCT06819436 is actively recruiting participants. Contact the research team at sidra_dow@yahoo.com for enrollment information.
Where is the NCT06819436 trial being conducted?
This trial is being conducted at Karachi, Pakistan.
Who is sponsoring the NCT06819436 clinical trial?
NCT06819436 is sponsored by Shaheed Mohtarma Benazir Bhutto Institue of Trauma. The trial plans to enroll 170 participants.