NCT06711614 FIRE-Diet: Food as an Intervention to Reduce the Effects of Woodsmoke Exposure on Respiratory Health
| NCT ID | NCT06711614 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of British Columbia |
| Condition | Healthy Individuals |
| Study Type | INTERVENTIONAL |
| Enrollment | 48 participants |
| Start Date | 2025-06-17 |
| Primary Completion | 2028-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 48 participants in total. It began in 2025-06-17 with a primary completion date of 2028-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Research suggests that consuming more fatty fish, fruits, and vegetables could potentially shield the lungs from the negative impacts of air pollution. The research team will look at whether a dietary intervention aimed at increasing intake of these foods can protect the lungs from woodsmoke as the air pollutant and look into how this works.
Eligibility Criteria
Inclusion Criteria: * Healthy, and specifically with no respiratory disease * Not taking any supplements, or willing to abstain from supplement use for 4-weeks prior to study start and the whole duration of the study, * Must currently consume, on average, less than 2 servings of fish per week and fewer than 5 servings of fruits and vegetables per day based on screening questionnaires. * Must have a null GSTM1 genotype determined at screening. * Must be able to provide a sufficient sputum sample during the screening visit. Exclusion Criteria: * Pregnant or planning to become pregnant during the study period. * Health conditions that would pose an unacceptable risk of dietary change, or conditions that are uncontrolled based on principal investigator's judgement. * Actively attempting to lose weight. * Frequent wood smoke exposure (e.g. at home or employment). * Unable to store provided meals and food safely. * Food allergies/intolerance or food aversion preventing adherence to the intervention diet, or unwillingness/medically unable to adjust diet in line with the intervention. * Relocation during the study period to an area which will prevent food delivery. * History of smoking tobacco, marijuana, or and other substance or vaping within the past 6 months, or having smoked the equivalent of 0.5 pack-years ever. * Body mass index (BMI) \<18.5, as determined during the in-person screening visit.
Contact & Investigator
Emily Brigham, MD
PRINCIPAL INVESTIGATOR
University of British Columbia
Frequently Asked Questions
Who can join the NCT06711614 clinical trial?
This trial is open to participants of all sexes, aged 19 Years or older, up to 40 Years, studying Healthy Individuals. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06711614 currently recruiting?
Yes, NCT06711614 is actively recruiting participants. Contact the research team at agustin.bueso@ubc.ca for enrollment information.
Where is the NCT06711614 trial being conducted?
This trial is being conducted at Vancouver, Canada.
Who is sponsoring the NCT06711614 clinical trial?
NCT06711614 is sponsored by University of British Columbia. The principal investigator is Emily Brigham, MD at University of British Columbia. The trial plans to enroll 48 participants.
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