NCT07618728 Feasibility of a Community-Based Multimodal Exercise Programme in Parkinson's Disease
| NCT ID | NCT07618728 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universidad Rey Juan Carlos |
| Condition | PARKINSON DISEASE (Disorder) |
| Study Type | INTERVENTIONAL |
| Enrollment | 64 participants |
| Start Date | 2025-09-08 |
| Primary Completion | 2026-06 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 64 participants in total. It began in 2025-09-08 with a primary completion date of 2026-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate the feasibility and preliminary effectiveness of a multimodal, group-based but individualised therapeutic exercise programme for people with Parkinson's disease delivered within a real-world community-based patient association setting. The primary objective is to assess the feasibility of implementing the programme, including recruitment, consent, adherence, intervention completion, acceptability, perceived exertion and safety. Secondary objectives are to obtain preliminary comparative information regarding the effects of the intervention on motor and non-motor symptoms, physical fitness, pain-related outcomes and exercise-induced hypoalgesia. This is a non-randomized sequential feasibility study including an intervention group participating in a 12-week multimodal exercise programme and a matched non-exercise control group maintaining usual activities. Outcomes will be assessed at baseline, post-intervention and 6-month follow-up.
Eligibility Criteria
Eligibility Criteria The eligibility criteria will be identical for both the experimental and control groups. However, this study will employ a sequential recruitment design. Participants for the control group will be recruited following the experimental group and will be matched (1:1 ratio) based on sex, age (± 5 years), and disease severity according to the Hoehn \& Yahr (H\&Y) scale. Inclusion Criteria: * Subjects diagnosed with Idiopathic Parkinson's Disease according to the UK Parkinson's Disease Society Brain Bank Diagnostic Criteria. * Subjects staged between 1 and 3 on the Hoehn \& Yahr Scale. For matching purposes, stage 1 includes stage 1.5, and stage 2 includes stage 2.5. Exclusion Criteria: * Subjects diagnosed with a neurological disease other than PD. * Those diagnosed with a cardiovascular, respiratory, or metabolic disease or other conditions that represent a contraindication to physical exercise. * Those who have suffered an exacerbation or hospitalization in the last three months prior to starting the assessment protocol or during the therapeutic intervention process. * Those who have received a course of steroids, intravenously or orally, six months prior to the start of the study or during the therapeutic intervention process. * Those with cognitive impairment (defined as a score \< 21 on the Montreal Cognitive Assessment, MoCA) or language impairments that prevent adequate communication, comprehension, or following of exercise instructions. * Participation in a structured, individualized strength and/or aerobic exercise program within the three months prior to enrollment.
Contact & Investigator
Mario González Iglesias, Physiotherapy
PRINCIPAL INVESTIGATOR
Universidad Rey Juan Carlos
Frequently Asked Questions
Who can join the NCT07618728 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying PARKINSON DISEASE (Disorder). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07618728 currently recruiting?
Yes, NCT07618728 is actively recruiting participants. Contact the research team at mario.gonzalez@urjc.es for enrollment information.
Where is the NCT07618728 trial being conducted?
This trial is being conducted at Alcorcón, Spain.
Who is sponsoring the NCT07618728 clinical trial?
NCT07618728 is sponsored by Universidad Rey Juan Carlos. The principal investigator is Mario González Iglesias, Physiotherapy at Universidad Rey Juan Carlos. The trial plans to enroll 64 participants.
Related Trials
Related Intelligence Guides
In-depth guides covering this condition's trials, eligibility, and what to expect.