NCT07351032 Understanding How Movements Are Transferred From Task to Task in Parkinson's Disease
| NCT ID | NCT07351032 |
| Status | Recruiting |
| Phase | — |
| Sponsor | McGill University |
| Condition | PARKINSON DISEASE (Disorder) |
| Study Type | INTERVENTIONAL |
| Enrollment | 24 participants |
| Start Date | 2025-11-18 |
| Primary Completion | 2026-05 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 24 participants in total. It began in 2025-11-18 with a primary completion date of 2026-05.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to understand how a specific brain area, the Posterior Parietal Cortex (PPC), plays a role in movement transfer from walking on a split-belt treadmill (SBT) to walking on the ground in people with Parkinson's disease (PwPD). Here, investigators will apply repeated transcranial magnetic stimulation (rTMS) to upregulate the PPC. Then, the differences in the gait parameters between pre- and post-interventions will be compared between the TMS-active and the TMS-sham.
Eligibility Criteria
Inclusion Criteria: * a confirmed diagnosis of idiopathic Parkinson's disease * absence of freezing of gait confirmed by a "No" answer to the second item of the New Freezing of Gait Questionnaire (NFOGQ) and no observation of FOG during a freezing provoking test * no other neurological diagnosis * no severe musculoskeletal/orthopedic or vestibular condition that interferes with walking and or significantly affects balance * no mild cognitive impairment (Montreal Cognitive Assessment ≥ 25) * able to walk independently and without assistive device for 30 minutes * no previous experience with split-belt treadmill. Exclusion Criteria: * severe dyskinesia that interacts with walking and balance hearing or visual impairment * observed inability to walk safely on a tied-belt treadmill * neurological disorders other than PD or other pathology (e.g., orthopedic) interfering with mobility. - contradiction for TMS * implanted deep brain stimulator.
Contact & Investigator
Caroline Paquette, PhD
PRINCIPAL INVESTIGATOR
McGill University
Frequently Asked Questions
Who can join the NCT07351032 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, studying PARKINSON DISEASE (Disorder). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07351032 currently recruiting?
Yes, NCT07351032 is actively recruiting participants. Contact the research team at hbcl@mcgill.ca for enrollment information.
Where is the NCT07351032 trial being conducted?
This trial is being conducted at Montreal, Canada.
Who is sponsoring the NCT07351032 clinical trial?
NCT07351032 is sponsored by McGill University. The principal investigator is Caroline Paquette, PhD at McGill University. The trial plans to enroll 24 participants.
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