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parkinson disease disorder

Total Trials
10
Recruiting Now
10
Trial Phases
Various

Parkinson's disease research has expanded from symptomatic management (dopaminergic drugs, DBS) toward neuroprotective and disease-modifying strategies targeting alpha-synuclein aggregation β€” the protein implicated in Lewy body pathology. Prodromal biomarker studies now aim to identify patients years before motor symptoms appear, when intervention may be most effective.

Trials test alpha-synuclein antibodies (prasinezumab, cinpanemab), GBA1 gene therapy, adaptive deep brain stimulation (aDBS), GLP-1 agonists (liraglutide, semaglutide), and nilotinib for neuroprotection. Skin biopsy and cerebrospinal fluid alpha-synuclein assays are emerging as enrollment biomarkers.

Disease-modifying trials often restrict enrollment to early-stage patients (Hoehn & Yahr 1–2.5) within a few years of diagnosis to capture sufficient disease duration for benefit detection.

Frequently Asked Questions — parkinson disease disorder Clinical Trials

How many clinical trials are currently recruiting for parkinson disease disorder?
ClinicalMetric currently tracks 10 actively recruiting clinical trials for parkinson disease disorder, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 10. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for parkinson disease disorder?
parkinson disease disorder research spans multiple clinical trial phases. Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a parkinson disease disorder clinical trial?
Eligibility criteria for parkinson disease disorder trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Top Sponsors
University of Cambridge 1 trial
University of Valencia 1 trial
University Hospital, Grenoble 1 trial
Shanghai University of Sport 1 trial
Cleveland State University 1 trial

Recruiting Clinical Trials

NCT07786116
Recruiting
The Role of METhanogens in the PROgression Of Parkinson's Disease and Related Neurological Conditions
Enrollment
215 pts
Location
United Kingdom
Sponsor
University of Cambridge
View Trial →
NCT07907302
Recruiting
Strength and Dual-Task on Sarcopenia in People With Parkinson's Disease
Enrollment
60 pts
Location
Spain
Sponsor
University of Valencia
View Trial →
NCT07427498
Recruiting
The Role of Priors in Hallucinatory Perception in Parkinson's Disease
Enrollment
60 pts
Location
France
Sponsor
University Hospital, Grenoble
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NCT07518290
Recruiting
Remotely Supervised Home-based Transcranial Temporal Interference Stimulation on Motor Symptoms in Parkinson's Disease
Enrollment
98 pts
Location
China
Sponsor
Shanghai University of Sport
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NCT07519096
Recruiting
Steady Together Fall Prevention Program in the Home
Enrollment
50 pts
Location
United States
Sponsor
Cleveland State University
View Trial →
NCT07725315
Recruiting
Investigating the Increased Risk of Falls in Individuals With Parkinson's Disease Treated With Deep Brain Stimulation
Enrollment
20 pts
Location
United States
Sponsor
University of Alabama at Birmi...
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NCT07679256
Recruiting
Integrated Digital and Neurogenic Exosome Biomarkers for Early Diagnosis of Parkinson's Disease: Development and Application
Enrollment
700 pts
Location
China
Sponsor
Fujian Medical University Unio...
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NCT07798271
Recruiting
Optimizing Adaptive DBS for Parkinson's Disease
Enrollment
35 pts
Location
United States
Sponsor
University of California, Davi...
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NCT07351032
Recruiting
Understanding How Movements Are Transferred From Task to Task in Parkinson's Disease
Enrollment
24 pts
Location
Canada
Sponsor
McGill University
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NCT07271927
Recruiting
Whole-Body Photobiomodulation for Motor and Cognitive Changes in Parkinson's Disease
Enrollment
15 pts
Location
South Korea
Sponsor
Pusan National University Yang...
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology