This study examines blood and lymph node cancers, which occur when white blood cells grow uncontrollably in lymphatic tissues or bone marrow. Researchers are investigating different subtypes of these cancers, including lymphoma and leukemia, to better understand how they develop and progress.
Key Objective: This family study may help researchers identify genetic and environmental factors that increase cancer risk, potentially leading to better prevention and early detection strategies.
Who to Consider: People with a personal or family history of lymphoproliferative disorders, including lymphoma, leukemia, or myeloma, should consider enrolling in this study.
Trial Parameters
Brief Summary
Blood and lymph node cancers can begin in either the lymphatic tissues (as in the case of lymphoma) or in the bone marrow (as with leukemia and myeloma), and they all are involved with the uncontrolled growth of white blood cells. There are many subtypes of these cancers, e.g., chronic lymphocytic leukemia and non-Hodgkin lymphoma. Since there is evidence that these cancers cluster in families, this study aims to understand how genetics and environmental exposures contribute to the development of these cancers.
Eligibility Criteria
At least 2 living, blood related relatives, affected with a lymphoproliferative disorder.