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Recruiting Phase 2 NCT06138275

Elranatamab in R/R Multiple Myeloma

Trial Parameters

Condition Refractory Multiple Myeloma
Sponsor Massachusetts General Hospital
Study Type INTERVENTIONAL
Phase Phase 2
Enrollment 32
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-03-08
Completion 2026-08-01
Interventions
Elranatamab

Brief Summary

This research is being done to see if the study drug, elranatamab, reduces the risk of disease progression (worsening disease) after idecabtagene vicleucel in relapsed refractory multiple myeloma.

Eligibility Criteria

Inclusion Criteria: * Participant has given voluntary signed written informed consent before performance of any study related procedure that is not part of normal medical care, with the understanding that consent may be withdrawn by the participant at any time without prejudice to their future medical care. * Eastern Cooperative Oncology Group (ECOG) performance status ≤ 1. * Male or female participants age ≥ 18 years * The effects of elranatamab on the developing human fetus are unknown. For this reason and because anti-BCMA bispecific antibodies are known to be teratogenic, women of child-bearing potential and men must agree to use adequate contraception (hormonal or barrier method of birth control; abstinence) prior to study entry and for the duration of study participation. Should a woman become pregnant or suspect she is pregnant while she or her partner is participating in this study, she should inform her treating physician immediately. Men treated or enrolled on this protocol m

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